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Tmco2 Gene Detail
Summary
  • Symbol
    Tmco2
  • Name
    transmembrane and coiled-coil domains 2
  • Synonyms
    1700028F16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916719
    NCBI Gene: 69469
Location & Maps
more
  • Sequence Map
    Chr4:121105651-121109226 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3576 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 56.80 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TMCO2, transmembrane and coiled-coil domains 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TMCO2, transmembrane and coiled-coil domains 2
    Orthology source: HomoloGene
  • Synonyms
    dJ39G22.2
  • Links
    NCBI Gene ID: 127391
    neXtProt AC: NX_Q7Z6W1

  • Chr Location
    1p34.2; chr1:40247901-40251693 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Tmco2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008912 VEGA Gene Model | MGI Sequence Detail 3576 C57BL/6J ±  kb
transcript OTTMUST00000020239 VEGA | MGI Sequence Detail 719 Not Applicable  
polypeptide OTTMUSP00000009277 VEGA | MGI Sequence Detail 187 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    17 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032341 transmembrane and coiled-coil domain-containing protein 2
  • InterPro Domains
    IPR031697 Transmembrane and coiled-coil domain-containing protein 2
Molecular
Reagents
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  • All nucleic 1
    cDNA 1

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory