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Commd10 Gene Detail
Summary
  • Symbol
    Commd10
  • Name
    COMM domain containing 10
  • Synonyms
    2310003A05Rik, DRWMS2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916706
    NCBI Gene: 69456
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46958783-47087995 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 24.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    570 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916706
protein coding gene Chr18:46958783-47234284 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024416
protein coding gene Chr18:45801161-45945305 (+)
A/J MGP_AJ_G0024382
protein coding gene Chr18:44137482-44273113 (+)
AKR/J MGP_AKRJ_G0024351
protein coding gene Chr18:45346502-45483126 (+)
BALB/cJ MGP_BALBcJ_G0024382
protein coding gene Chr18:44245768-44376324 (+)
C3H/HeJ MGP_C3HHeJ_G0024149
protein coding gene Chr18:45439634-45576985 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024827
protein coding gene Chr18:47412952-47547679 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022261
protein coding gene Chr18:43943494-44069609 (+)
CAST/EiJ MGP_CASTEiJ_G0023624
protein coding gene Chr18:45386036-45520337 (+)
CBA/J MGP_CBAJ_G0024118
protein coding gene Chr18:48693841-48847632 (+)
DBA/2J MGP_DBA2J_G0024248
protein coding gene Chr18:43744487-43875413 (+)
FVB/NJ MGP_FVBNJ_G0024215
protein coding gene Chr18:43312416-43441617 (+)
LP/J MGP_LPJ_G0024333
protein coding gene Chr18:45864950-46004430 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024246
protein coding gene Chr18:50056483-50200631 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024874
protein coding gene Chr18:45277504-45420245 (+)
PWK/PhJ MGP_PWKPhJ_G0023367
protein coding gene Chr18:43894974-44027472 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023173
protein coding gene Chr18:45449048-45587653 (+)
WSB/EiJ MGP_WSBEiJ_G0023687
protein coding gene Chr18:45170008-45309320 (+)



Homology
more
  • Human Ortholog
    COMMD10, COMM domain containing 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COMMD10, COMM domain containing 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PTD002
  • Links
    NCBI Gene ID: 51397
    neXtProt AC: NX_Q9Y6G5
    UniProt: Q9Y6G5

  • Chr Location
    5q23.1; chr5:116084592-116446462 (+)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    160 phenotypes from multigenic genotypes
    1 images
    269 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69456 NCBI Gene Model | MGI Sequence Detail 129213 C57BL/6J ±  kb
transcript NM_178377 RefSeq | MGI Sequence Detail 1550 C57BL/6  
polypeptide Q8JZY2 UniProt | EBI | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147306, MGI:2449945
References
more
  • Summaries
    All 293
    Diseases 3
    Gene Ontology 1
    Phenotypes 269
  • Earliest
    J:140234 Ogilvy S, et al., Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. Blood. 1999 Sep 15;94(6):1855-63
  • Latest
    J:271310 Dolch A, et al., IL-10 signaling in dendritic cells is required for tolerance induction in a murine model of allergic airway inflammation. Eur J Immunol. 2019 Feb;49(2):302-312

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory