About   Help   FAQ
Jsrp1
Gene Detail
Symbol

Name
ID
Jsrp1
junctional sarcoplasmic reticulum protein 1
MGI:1916700
Synonyms
2300003C06Rik, 2310032K21Rik, JP45, JP-45
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:80808498-80813498 bp, - strand
From VEGA annotation of GRCm38

  5001 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12422  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Gene Tree: Jsrp1

Human
homologs
Human Homolog JSRP1, junctional sarcoplasmic reticulum protein 1
NCBI Gene ID 126306
neXtProt AC  NX_Q96MG2
Human Synonyms  JP45, JP-45
Human Chr (Location)  19p13.3; chr19:2252251-2256423 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit muscle weakness, abnormal voluntary movement and abnormal muscle physiology.
 
Interactions
Jsrp1 interacts with 6 markers (Mir138-1, Mir138-2, Mir1894, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process protein localization to membrane, regulation of ryanodine-sensitive calcium-release channel activity, ...
Component endoplasmic reticulum, membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (19)    Tissues (9)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 8
Western blot 11
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(11) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000042544 (Evidence)
Ensembl Gene ModelENSMUSG00000020216 (Evidence)
Entrez Gene71912 (Evidence)
UniGene45137
DFCITC1586950, TC1599487
DoTSDT.522150, DT.97356975
NIA Mouse Gene IndexU032023
Consensus CDS ProjectCCDS24034.2
International Mouse Knockout Project StatusJsrp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042544 VEGA Gene Model | MGI Sequence Detail 5001 C57BL/6J ±  kb
transcript OTTMUST00000112163 VEGA | MGI Sequence Detail 1108 Not Applicable 
polypeptide OTTMUSP00000062925 VEGA | MGI Sequence Detail 332 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026178 Junctional sarcoplasmic reticulum protein 1
Protein Ontology PR:000009228 junctional sarcoplasmic reticulum protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:196755 Delbono O, et al., Endogenously determined restriction of food intake overcomes excitation-contraction uncoupling in JP45KO mice with aging. Exp Gerontol. 2012 Apr;47(4):304-16
All references(31)
Other
accession IDs
MGI:1919162

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory