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Wdfy1 Gene Detail
Summary
  • Symbol
    Wdfy1
  • Name
    WD repeat and FYVE domain containing 1
  • Synonyms
    1700013B03Rik, 1700120F24Rik, Jr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916618
    NCBI Gene: 69368
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:79702262-79776047 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 40.94 cM, cytoband C4
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    692 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916618
protein coding gene Chr1:79702262-79776143 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016206
protein coding gene Chr1:80504300-80577988 (-)
A/J MGP_AJ_G0016189
protein coding gene Chr1:77655002-77724121 (-)
AKR/J MGP_AKRJ_G0016146
protein coding gene Chr1:79794797-79866872 (-)
BALB/cJ MGP_BALBcJ_G0016144
protein coding gene Chr1:77741890-77810889 (-)
C3H/HeJ MGP_C3HHeJ_G0015974
protein coding gene Chr1:80139137-80213401 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016597
protein coding gene Chr1:83615751-83685074 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014317
protein coding gene Chr1:73029699-73096569 (-)
CAST/EiJ MGP_CASTEiJ_G0015559
protein coding gene Chr1:79514701-79582082 (-)
CBA/J MGP_CBAJ_G0015948
protein coding gene Chr1:86307939-86383175 (-)
DBA/2J MGP_DBA2J_G0016049
protein coding gene Chr1:76982684-77049036 (-)
FVB/NJ MGP_FVBNJ_G0016052
protein coding gene Chr1:76112076-76182460 (-)
LP/J MGP_LPJ_G0016121
protein coding gene Chr1:81644047-81718260 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016072
protein coding gene Chr1:89568768-89641399 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016644
protein coding gene Chr1:79875509-79950210 (-)
PWK/PhJ MGP_PWKPhJ_G0015345
protein coding gene Chr1:76389351-76460259 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015123
protein coding gene Chr1:79204110-79270545 (-)
WSB/EiJ MGP_WSBEiJ_G0015620
protein coding gene Chr1:79698552-79769197 (-)



Homology
more
  • Human Ortholog
    WDFY1, WD repeat and FYVE domain containing 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    WDFY1, WD repeat and FYVE domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FENS1, FENS-1, WDF1, ZFYVE17
  • Links
    NCBI Gene ID: 57590
    neXtProt AC: NX_Q8IWB7
    UniProt: Q8IWB7

  • Chr Location
    2q36.1; chr2:223875343-223945387 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Wdfy1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69368 NCBI Gene Model | MGI Sequence Detail 73786 C57BL/6J ±  kb
transcript NM_001111279 RefSeq | MGI Sequence Detail 4566 C57BL/6  
polypeptide E9Q4P1 UniProt | EBI | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 15
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920857
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:255082 Kurogi S, et al., Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. Sci Rep. 2017 Jan 20;7:40692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory