About   Help   FAQ
Lrrc51 Gene Detail
Summary
  • Symbol
    Lrrc51
  • Name
    leucine rich repeat containing 51
  • Synonyms
    1700008D07Rik, Lrtomt
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916608
    NCBI Gene: 69358
  • Gene Overview
    MyGene.info: LRTOMT
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:101912984-101933895 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.69 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916608
 protein coding gene Chr7:101912984-101933923 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032594
 protein coding gene Chr7:104930072-104954837 (-)
A/J MGP_AJ_G0032570
 protein coding gene Chr7:102257623-102278495 (-)
AKR/J MGP_AKRJ_G0032506
 protein coding gene Chr7:104703137-104726388 (-)
BALB/cJ MGP_BALBcJ_G0032581
 protein coding gene Chr7:101955738-101976307 (-)
C3H/HeJ MGP_C3HHeJ_G0032295
 protein coding gene Chr7:105077095-105098351 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033078
 protein coding gene Chr7:108882825-108916885 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030072
 protein coding gene Chr7:104620203-104643301 (-)
CAST/EiJ MGP_CASTEiJ_G0031621
 protein coding gene Chr7:96635052-96657083 (-)
CBA/J MGP_CBAJ_G0032261
 protein coding gene Chr7:112657022-112680082 (-)
DBA/2J MGP_DBA2J_G0032413
 protein coding gene Chr7:100588128-100609409 (-)
FVB/NJ MGP_FVBNJ_G0032369
 protein coding gene Chr7:100369207-100390131 (-)
LP/J MGP_LPJ_G0032502
 protein coding gene Chr7:106247890-106272393 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032403
 protein coding gene Chr7:113981787-114005291 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033100
 protein coding gene Chr7:103974236-103998939 (-)
PWK/PhJ MGP_PWKPhJ_G0031339
 protein coding gene Chr7:93699986-93721259 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031183
 protein coding gene Chr7:91272106-91296200 (-)
WSB/EiJ MGP_WSBEiJ_G0031738
 protein coding gene Chr7:104663913-104688077 (-)



Homology
more
  • Human Ortholog
    LRTOMT, leucine rich transmembrane and O-methyltransferase domain containing
  • Vertebrate Orthologs
    6
  • Human Ortholog
    LRTOMT, leucine rich transmembrane and O-methyltransferase domain containing
    Orthology source: HGNC
  • Synonyms
    CFAP111, DFNB63, LRRC51
  • Links
    NCBI Gene ID: 220074
    neXtProt AC: NX_Q8WZ04, NX_Q96E66
    UniProt: Q8WZ04, Q96E66

  • Chr Location
    11q13.4; chr11:72079982-72110782 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human LRTOMT associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    36
  • Chemically induced (other)
    1
  • Gene trapped
    31
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Lrrc51
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    19 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    23
  • Tissues
    12
  • cDNA Data
    5
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064307 Ensembl Gene Model | MGI Sequence Detail 20912 C57BL/6J ±  kb
transcript ENSMUST00000078448 Ensembl | MGI Sequence Detail 873 Not Applicable  
polypeptide ENSMUSP00000077543 Ensembl | MGI Sequence Detail 192 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 16
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
12/04/2018
MGI 6.13 		The Jackson Laboratory