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Necab1 Gene Detail
Summary
  • Symbol
    Necab1
  • Name
    N-terminal EF-hand calcium binding protein 1
  • Synonyms
    1700003H21Rik, Efcbp1, NECAB1, STIP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916602
    NCBI Gene: 69352
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:14952245-15149794 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 6.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916602
protein coding gene Chr4:14952245-15149804 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028070
protein coding gene Chr4:11776153-11977387 (-)
A/J MGP_AJ_G0028028
protein coding gene Chr4:11495227-11697720 (-)
AKR/J MGP_AKRJ_G0027993
protein coding gene Chr4:11679762-11888184 (-)
BALB/cJ MGP_BALBcJ_G0028039
protein coding gene Chr4:11416863-11627021 (-)
C3H/HeJ MGP_C3HHeJ_G0027769
protein coding gene Chr4:11844743-12035982 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028482
protein coding gene Chr4:12303191-12521575 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025824
protein coding gene Chr4:10749014-10926573 (-)
CAST/EiJ MGP_CASTEiJ_G0027224
protein coding gene Chr4:11641672-11834010 (-)
CBA/J MGP_CBAJ_G0027742
protein coding gene Chr4:12548766-12757896 (-)
DBA/2J MGP_DBA2J_G0027885
protein coding gene Chr4:11365859-11552202 (-)
FVB/NJ MGP_FVBNJ_G0027851
protein coding gene Chr4:11138357-11320171 (-)
LP/J MGP_LPJ_G0027994
protein coding gene Chr4:11885786-12087535 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027884
protein coding gene Chr4:12911684-13114964 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028541
protein coding gene Chr4:11688212-11889677 (-)
PWK/PhJ MGP_PWKPhJ_G0026944
protein coding gene Chr4:11317091-11504787 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026773
protein coding gene Chr4:11562331-11756155 (-)
WSB/EiJ MGP_WSBEiJ_G0027301
protein coding gene Chr4:11717207-11909154 (-)



Homology
more
  • Human Ortholog
    NECAB1, N-terminal EF-hand calcium binding protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NECAB1, N-terminal EF-hand calcium binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EFCBP1, STIP-1
  • Links
    NCBI Gene ID: 64168
    neXtProt AC: NX_Q8N987
    UniProt: Q8N987

  • Chr Location
    8q21.3; chr8:90791693-90959402 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040536 Ensembl Gene Model | MGI Sequence Detail 197550 C57BL/6J ±  kb
transcript ENSMUST00000041606 Ensembl | MGI Sequence Detail 4922 Not Applicable  
polypeptide ENSMUSP00000038165 Ensembl | MGI Sequence Detail 352 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory