Fam24b MGI Mouse Gene Detail - MGI:1916568 - family with sequence similarity 24 member B

Symbol

Fam24b
Name

family with sequence similarity 24 member B
Synonyms

1700007K09Rik

Feature Type

protein coding gene
IDs

MGI:1916568
NCBI Gene: 69318
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr7:130927673-130931245 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 73.84 cM, cytoband F4
Mapping Data

2 experiments

SNPs within 2kb

11 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916568	protein coding gene	Chr7:130927136-130933163 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0033100	protein coding gene	Chr7:135950053-135953955 (-)
A/J	MGP_AJ_G0033082	protein coding gene	Chr7:132236518-132240426 (-)
AKR/J	MGP_AKRJ_G0033014	protein coding gene	Chr7:135745559-135751160 (-)
BALB/cJ	MGP_BALBcJ_G0033083	protein coding gene	Chr7:131925392-131933301 (-)
C3H/HeJ	MGP_C3HHeJ_G0032797	protein coding gene	Chr7:135599952-135603521 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0033594	protein coding gene	Chr7:141131630-141137398 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030565	protein coding gene	Chr7:133516039-133519512 (-)
CAST/EiJ	MGP_CASTEiJ_G0032127	protein coding gene	Chr7:127453184-127456908 (-)
CBA/J	MGP_CBAJ_G0032770	protein coding gene	Chr7:146028572-146032316 (-)
DBA/2J	MGP_DBA2J_G0032922	protein coding gene	Chr7:130222985-130226961 (-)
FVB/NJ	MGP_FVBNJ_G0032875	protein coding gene	Chr7:130089893-130093993 (-)
LP/J	MGP_LPJ_G0033016	protein coding gene	Chr7:137443141-137446871 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032907	protein coding gene	Chr7:146951512-146955084 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033614	protein coding gene	Chr7:134742599-134746179 (-)
PWK/PhJ	MGP_PWKPhJ_G0031833	protein coding gene	Chr7:123258419-123262518 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0031679	protein coding gene	Chr7:121514710-121518190 (-)
WSB/EiJ	MGP_WSBEiJ_G0032238	protein coding gene	Chr7:135640318-135645119 (-)

Human Ortholog

FAM24A, family with sequence similarity 24 member A

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM24A, family with sequence similarity 24 member A
Links

HGNC:23470

NCBI Gene ID: 118670

neXtProt AC: NX_A6NFZ4

UniProt: A6NFZ4
Chr Location

10q26.13; chr10:122910595-122913111 (+) GRCh38.p7

Human Ortholog

FAM24B, family with sequence similarity 24 member B
Links

HGNC:23475

NCBI Gene ID: 196792

neXtProt AC: NX_Q8N5W8

UniProt: Q8N5W8
Chr Location

10q26.13; chr10:122849094-122879641 (-) GRCh38.p7

Alliance of Genome Resources

Fam24b stringent orthology
2 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: FAM24A, FAM24B
Gene Tree

Fam24b

less

Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
3 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Endonuclease-mediated

1
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

8 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

less

All GO Annotations

1
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

672
cDNA Data

9

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

Fam24b interacts with 5 markers (Mir98, Mirlet7a-1, Mirlet7b, ...) View All

less

All Sequences

33
RefSeq

4
UniProt

1
CCDS

CCDS21912.1

Ensembl

ENSMUSG00000030858 (Evidence)
NCBI Gene

69318

			Length	Strain/Species	Flank
genomic	ENSMUSG00000030858	Ensembl Gene Model \| MGI Sequence Detail	3573	C57BL/6J	± kb
transcript	ENSMUST00000188899	Ensembl \| MGI Sequence Detail	680	Not Applicable
polypeptide	ENSMUSP00000139545	Ensembl \| MGI Sequence Detail	119	Not Applicable

less

UniProt

1 Sequence
InterPro Domains

IPR028122 FAM24 family

less

All nucleic 9

cDNA 9

Microarray probesets 3

Summaries

All 23

Gene Ontology 1

Phenotypes 3
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Fam24b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr75181	Chr7:130931256-130931259 (-)	-13 bp
Tssr75180	Chr7:130931236-130931251 (-)	1 bp
Tssr75179	Chr7:130931222-130931233 (-)	17 bp
Tssr75178	Chr7:130931199-130931215 (-)	38 bp
Tssr75177	Chr7:130931190-130931194 (-)	53 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 06/23/2022 MGI 6.20