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Pacrg Gene Detail
Summary
  • Symbol
    Pacrg
  • Name
    PARK2 co-regulated
  • Synonyms
    1700008H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916560
    NCBI Gene: 69310
  • Gene Overview
    MyGene.info: PACRG
Location & Maps
more
  • Sequence Map
    Chr17:10403012-10840311 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      437300 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 7.80 cM, cytoband A2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PACRG, PARK2 coregulated
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PACRG, PARK2 coregulated
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GLUP, HAK005771, PARK2CRG
  • Links
    NCBI Gene ID: 135138
    neXtProt AC: NX_Q96M98

  • Chr Location
    6q26; chr6:162727084-163315492 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 16212
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PACRG
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    95 phenotype references
  • All Mutations and Alleles
    129
  • Endonuclease-mediated
    1
  • Gene trapped
    121
  • Radiation induced
    5
  • Spontaneous
    1
  • Transgenic
    1
  • Genomic Mutations
    6 involving Pacrg
  • Incidental Mutations
Along with altered levele of the Qki transcript, both Pacrg and Park2 are inactivated as a result of a 1.85 Mb deletion in the in the quaking mouse. The quaking mouse is a spontaneous dysmyelinating mutant that demonstrates abnormal locomotion, tremor, and tonic-clonic seizures.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031249 VEGA Gene Model | MGI Sequence Detail 437300 C57BL/6J ±  kb
transcript OTTMUST00000077414 VEGA | MGI Sequence Detail 1475 Not Applicable  
polypeptide OTTMUSP00000040936 VEGA | MGI Sequence Detail 241 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1340 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    Genomic 3
    cDNA 20

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 95
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:195051 Thumberger T, et al., Ciliary and non-ciliary expression and function of PACRG during vertebrate development. Cilia. 2012;1(1):13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory