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Efcab9 Gene Detail
Summary
  • Symbol
    Efcab9
  • Name
    EF-hand calcium binding domain 9
  • Synonyms
    1700007I06Rik, 4930403C08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916556
    NCBI Gene: 69306
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:32522751-32532081 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 18.97 cM, cytoband A5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916556
protein coding gene Chr11:32522733-32533270 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018136
protein coding gene Chr11:30758080-30772241 (-)
A/J MGP_AJ_G0018109
protein coding gene Chr11:29583622-29592885 (-)
AKR/J MGP_AKRJ_G0018073
protein coding gene Chr11:30521082-30530459 (-)
BALB/cJ MGP_BALBcJ_G0018078
protein coding gene Chr11:29775749-29785130 (-)
C3H/HeJ MGP_C3HHeJ_G0017891
protein coding gene Chr11:30459900-30470672 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018532
protein coding gene Chr11:31763334-31774109 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016187
protein coding gene Chr11:28107829-28117403 (-)
CAST/EiJ MGP_CASTEiJ_G0017455
protein coding gene Chr11:30497263-30514676 (-)
CBA/J MGP_CBAJ_G0017864
protein coding gene Chr11:33272781-33284609 (-)
DBA/2J MGP_DBA2J_G0017974
protein coding gene Chr11:29376805-29386862 (-)
FVB/NJ MGP_FVBNJ_G0017968
protein coding gene Chr11:29202424-29211752 (-)
LP/J MGP_LPJ_G0018046
protein coding gene Chr11:31019893-31031027 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017992
protein coding gene Chr11:34246614-34257628 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018571
protein coding gene Chr11:30650735-30661782 (-)
PWK/PhJ MGP_PWKPhJ_G0017236
protein coding gene Chr11:29533559-29544026 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017028
protein coding gene Chr11:30348923-30360059 (-)
WSB/EiJ MGP_WSBEiJ_G0017504
protein coding gene Chr11:30283418-30296746 (-)



Homology
more
  • Human Ortholog
    EFCAB9, EF-hand calcium binding domain 9
  • Vertebrate Orthologs
    8
  • Human Ortholog
    EFCAB9, EF-hand calcium binding domain 9
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 285588
    neXtProt AC: NX_A8MZ26
    UniProt: A8MZ26

  • Chr Location
    5q35.1; chr5:172188061-172203454 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    1
  • Genomic Mutations
    1 involving Efcab9
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044056 Ensembl Gene Model | MGI Sequence Detail 9331 C57BL/6J ±  kb
transcript ENSMUST00000054327 Ensembl | MGI Sequence Detail 754 Not Applicable  
polypeptide ENSMUSP00000060205 Ensembl | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGI:1921194
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:276402 Hwang JY, et al., Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility. Cell. 2019 May 30;177(6):1480-1494.e19

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory