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Dcps Gene Detail
Summary
  • Symbol
    Dcps
  • Name
    decapping enzyme, scavenger
  • Synonyms
    1700001E16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916555
    NCBI Gene: 69305
  • Gene Overview
    MyGene.info: DCPS
Location & Maps
more
  • Sequence Map
    Chr9:35124408-35176061 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      51654 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DCPS, decapping enzyme, scavenger
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCPS, decapping enzyme, scavenger
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ARS, DCS1, HINT5, HINT-5, HSL1, HSPC015
  • Links
    NCBI Gene ID: 28960
    neXtProt AC: NX_Q96C86

  • Chr Location
    11q24.2; chr11:126303752-126345754 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human DCPS associations

Human Disease Mouse Models
       Al-Raqad Syndrome; ARS   OMIM: 616459
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
A mutant mouse line was generated from gene-trapped ES cells, but no phenotypic information is available.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031937 VEGA Gene Model | MGI Sequence Detail 51654 C57BL/6J ±  kb
transcript OTTMUST00000079214 VEGA | MGI Sequence Detail 1274 Not Applicable  
polypeptide OTTMUSP00000042219 VEGA | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    396 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142921
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:201100 Van Meerbeke JP, et al., The DcpS inhibitor RG3039 improves motor function in SMA mice. Hum Mol Genet. 2013 Oct 15;22(20):4074-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory