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Sec62 Gene Detail
Summary
  • Symbol
    Sec62
  • Name
    SEC62 homolog (S. cerevisiae)
  • Synonyms
    3100002M17Rik, Dtrp1, HTP1, SEC62, Tloc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916526
    NCBI Gene: 69276
  • Gene Overview
    MyGene.info: SEC62
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:30792875-30821263 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 14.29 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    190 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916526
protein coding gene Chr3:30792765-30821263 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027127
protein coding gene Chr3:28295636-28326409 (+)
A/J MGP_AJ_G0027087
protein coding gene Chr3:27927478-27955834 (+)
AKR/J MGP_AKRJ_G0027056
protein coding gene Chr3:28357481-28385831 (+)
BALB/cJ MGP_BALBcJ_G0027099
protein coding gene Chr3:27618896-27647354 (+)
C3H/HeJ MGP_C3HHeJ_G0026841
protein coding gene Chr3:28377709-28406253 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027545
protein coding gene Chr3:29804286-29832595 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024906
protein coding gene Chr3:25841057-25869867 (+)
CAST/EiJ MGP_CASTEiJ_G0026295
protein coding gene Chr3:28296375-28324932 (+)
CBA/J MGP_CBAJ_G0026819
protein coding gene Chr3:30553471-30583066 (+)
DBA/2J MGP_DBA2J_G0026953
protein coding gene Chr3:27477569-27505815 (+)
FVB/NJ MGP_FVBNJ_G0026921
protein coding gene Chr3:26926498-26955780 (+)
LP/J MGP_LPJ_G0027064
protein coding gene Chr3:28994616-29024160 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026941
protein coding gene Chr3:33137542-33169365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027604
protein coding gene Chr3:28095892-28124177 (+)
PWK/PhJ MGP_PWKPhJ_G0026028
protein coding gene Chr3:26996290-27025000 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025840
protein coding gene Chr3:27628322-27656633 (+)
WSB/EiJ MGP_WSBEiJ_G0026369
protein coding gene Chr3:28196009-28225415 (+)



Homology
more
  • Human Ortholog
    SEC62, SEC62 homolog, preprotein translocation factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC62, SEC62 homolog, preprotein translocation factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Dtrp1, HTP1, TLOC1, TP-1
  • Links
    NCBI Gene ID: 7095
    neXtProt AC: NX_Q99442
    UniProt: Q99442

  • Chr Location
    3q26.2; chr3:169966792-169998373 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    25
  • Endonuclease-mediated
    1
  • Gene trapped
    23
  • Radiation induced
    1
  • Genomic Mutations
    1 involving Sec62
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027706 Ensembl Gene Model | MGI Sequence Detail 28389 C57BL/6J ±  kb
transcript ENSMUST00000029256 Ensembl | MGI Sequence Detail 3967 Not Applicable  
polypeptide ENSMUSP00000029256 Ensembl | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 10
Other
Accession IDs
less
MGI:2139808, MGI:2139994
References
more
  • Summaries
    All 31
    Diseases 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197701 Lang S, et al., Different effects of Sec61alpha, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci. 2012 Apr 15;125(Pt 8):1958-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory