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Rfc3 Gene Detail
Summary
  • Symbol
    Rfc3
  • Name
    replication factor C (activator 1) 3
  • Synonyms
    2810416I22Rik, 38kDa, 38kDa, Recc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916513
    NCBI Gene: 69263
  • Gene Overview
    MyGene.info: RFC3
Location & Maps
more
  • Sequence Map
    Chr5:151642756-151651242 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8487 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 90.18 cM, cytoband G3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RFC3, replication factor C subunit 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RFC3, replication factor C subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RFC38
  • Links
    NCBI Gene ID: 5983
    neXtProt AC: NX_P40938

  • Chr Location
    13q13.2; chr13:33818049-33973946 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Gene trapped
    1
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028751 VEGA Gene Model | MGI Sequence Detail 8487 C57BL/6J ±  kb
transcript OTTMUST00000071228 VEGA | MGI Sequence Detail 1317 Not Applicable  
polypeptide OTTMUSP00000036453 VEGA | MGI Sequence Detail 356 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013907 replication factor C subunit 3
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 69
    cDNA 69

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-13827, MGI:2141068, MGI:97893
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:40897 Bunz F, et al., cDNAs encoding the large subunit of human replication factor C. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11014-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory