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Elf2 Gene Detail
Summary
  • Symbol
    Elf2
  • Name
    E74-like factor 2
  • Synonyms
    2610036A20Rik, A230104O07Rik, NERF-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916507
    NCBI Gene: 69257
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:51160141-51248084 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 22.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2434 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916507
 protein coding gene Chr3:51160141-51248101 (-)
129S1/SvImJ ENSMUSG00200000344
 protein coding gene Chr3:47983980-48054731 (-)
A/J ENSMUSG00195000695
 protein coding gene Chr3:47946554-48017304 (-)
AKR/J ENSMUSG00220015496
 protein coding gene Chr3:48001048-48071783 (-)
BALB/cJ ENSMUSG00180000256
 protein coding gene Chr3:48023854-48094607 (-)
C3H/HeJ ENSMUSG00175002066
 protein coding gene Chr3:47854687-47925434 (-)
C57BL/6NJ ENSMUSG00215000509
 protein coding gene Chr3:48293362-48364111 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024972
 protein coding gene Chr3:44901511-44988085 (-)
CAST/EiJ ENSTCUG00005009352
 protein coding gene Chr3:47672228-47744138 (-)
CBA/J ENSMUSG00210000503
 protein coding gene Chr3:47967559-48038319 (-)
DBA/2J ENSMUSG00185000223
 protein coding gene Chr3:48208896-48279647 (-)
FVB/NJ ENSMUSG00205009260
 protein coding gene Chr3:47186902-47257663 (-)
JF1/MsJ ENSUMUG00000016223
 protein coding gene Chr3:47623042-47695073 (-)
LP/J ENSMUSG00230000242
 protein coding gene Chr3:50156195-50226943 (-)
NOD/ShiLtJ ENSMUSG00190000187
 protein coding gene Chr3:48338844-48409585 (-)
NZO/HlLtJ ENSMUSG00225016079
 protein coding gene Chr3:52783451-52854190 (-)
PWK/PhJ ENSLUMG00010009690
 protein coding gene Chr3:47789047-47861078 (-)
SPRET/EiJ ENSMSPG00010006887
 protein coding gene Chr3:48448458-48519583 (-)
WSB/EiJ ENSIUOG00005000349
 protein coding gene Chr3:48135697-48206378 (-)



Homology
more
  • Human Ortholog
    ELF2, E74 like ETS transcription factor 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELF2, E74 like ETS transcription factor 2
  • Synonyms
    EU32, NERF, NERF-1A, NERF-1a,b, NERF-1B, NERF-2
  • Links
    NCBI Gene ID: 1998
    UniProt: Q15723

  • Chr Location
    4q31.1; chr4:139028112-139177915 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    922
  • Tissues
    209
  • cDNA Data
    19
  • Literature Summary
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037174 Ensembl Gene Model | MGI Sequence Detail 87944 C57BL/6J ±  kb
transcript ENSMUST00000194641 Ensembl | MGI Sequence Detail 5919 Not Applicable  
polypeptide ENSMUSP00000141197 Ensembl | MGI Sequence Detail 593 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 21
    Primer pair 3
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139969, MGI:2140032
References
more
  • Summaries
    All 81
    Developmental Gene Expression 16
    Diseases 1
    Gene Ontology 8
    Phenotypes 19
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:390299 Wang DM, et al., Protocol to generate endothelial cell-specific knockout mouse models using Cas9/Cdh5-Cre mice coupled with sgRNA. STAR Protoc. 2026 Jun 19;7(2):104551
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory