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Elf2
Gene Detail
Symbol

Name
ID
Elf2
E74-like factor 2
MGI:1916507
Synonyms
2610036A20Rik, A230104O07Rik, NERF-2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
22.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:51252720-51340663 bp, - strand
From VEGA annotation of GRCm38

  87944 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ELF2
Gene Tree: Elf2

Human
homologs
ELF2, E74-like factor 2 (ets domain transcription factor)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1998
neXtProt AC: NX_Q15723

Human Synonyms: EU32, NERF, NERF-1A, NERF-1a,b, NERF-1B, NERF-2

Human Chr (Location): 4q28; chr4:139057717-139177218 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(18) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Elf2 interacts with 224 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell differentiation, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleoplasm, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (314)    Tissues (204)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 305
RT-PCR 9
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA ELF2 ; Xenbase elf2 ; ZFIN elf2b    NEW 
Molecular
reagents
All nucleic(23) cDNA(21) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000051593 (Evidence)
Ensembl Gene Model ENSMUSG00000037174 (Evidence)
Entrez Gene 69257 (Evidence)
DFCI TC1625844, TC1576043, TC1602465, TC1588789, TC1586017
DoTS DT.101184856, DT.101253274, DT.101383894, DT.101383893, DT.534025, DT.94274553, DT.91330434, DT.97336704
Consensus CDS Project CCDS17337.1, CCDS71240.1, CCDS71241.1, CCDS71242.1
International Mouse Phenotyping Consortium Status Elf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051593 VEGA Gene Model | MGI Sequence Detail 87944 C57BL/6J ±  kb
transcript OTTMUST00000050295 VEGA | MGI Sequence Detail 5919 Not Applicable 
polypeptide OTTMUSP00000023461 VEGA | MGI Sequence Detail 593 Not Applicable 

For the selected sequences
All sequences(114) RefSeq(18) UniProt(12)
Polymorphisms
SNPs within 2kb(605 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000418 Ets domain
InterPro IPR022084 Transcription factor Elf, N-terminal
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007021 ETS-related transcription factor Elf-2
References
(Earliest) J:115181 Wilkinson DA, et al., Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia. Leukemia. 1997 Jan;11(1):86-96
(Latest) J:179397 Schachterle W, et al., ETS-dependent regulation of a distal Gata4 cardiac enhancer. Dev Biol. 2012 Jan 15;361(2):439-49
All references(46)
Other
accession IDs
MGI:2139969, MGI:2140032

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory