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Elf2
Gene Detail
 Symbol
Name
ID
Elf2
E74-like factor 2
MGI:1916507
Synonyms 2610036A20Rik, A230104O07Rik, NERF-2
Feature Type protein coding gene
Genetic Map
Chromosome 3
22.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:51255665-51340658 bp, - strand
From VEGA annotation of GRCm38

  84994 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Elf2

Human
homologs
Human Homolog ELF2, E74-like factor 2 (ets domain transcription factor)
NCBI Gene ID 1998
neXtProt AC  NX_Q15723
Human Synonyms  EU32, NERF, NERF-1A, NERF-1a,b, NERF-1B, NERF-2
Human Chr (Location)  4q28; chr4:139057717-139177218 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(18) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Elf2 interacts with 224 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell differentiation, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleus
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (314)    Tissues (204)    Images (50)
Theiler Stages: 2, 3, 4, 5, 17, 18, 19, 21, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 305
RT-PCR 9
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(20) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000021235 (Evidence)
Ensembl Gene ModelENSMUSG00000037174 (Evidence)
Entrez Gene69257 (Evidence)
DFCITC1576043, TC1586017, TC1588789, TC1602465, TC1625844
DoTSDT.534025, DT.101184856, DT.101383893, DT.101383894, DT.91330434, DT.94274553, DT.97336704
Consensus CDS ProjectCCDS17337.1, CCDS71240.1, CCDS71241.1, CCDS71242.1
International Mouse Knockout Project StatusElf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021235 VEGA Gene Model | MGI Sequence Detail 84994 C57BL/6J ±  kb
transcript OTTMUST00000050295 VEGA | MGI Sequence Detail 2877 Not Applicable 
polypeptide OTTMUSP00000023461 VEGA | MGI Sequence Detail 593 Not Applicable 

For the selected sequences
All sequences(95) RefSeq(20) UniProt(9)
Polymorphisms SNPs within 2kb(580 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000418 Ets domain
InterPro IPR022084 Transcription factor Elf, N-terminal
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007021 ETS-related transcription factor Elf-2
References (Earliest) J:115181 Wilkinson DA, et al., Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia. Leukemia. 1997 Jan;11(1):86-96
(Latest) J:179397 Schachterle W, et al., ETS-dependent regulation of a distal Gata4 cardiac enhancer. Dev Biol. 2012 Jan 15;361(2):439-49
All references(48)
Other
accession IDs
MGI:2139969, MGI:2140032

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory