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Elf2
Gene Detail
Symbol

Name
ID
Elf2
E74-like factor 2
MGI:1916507
Synonyms
2610036A20Rik, A230104O07Rik, NERF-2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
22.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:51252720-51340663 bp, - strand
From VEGA annotation of GRCm38

  87944 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Elf2

Human
homologs
Human Homolog   ELF2, E74-like factor 2 (ets domain transcription factor)
NCBI Gene ID 1998
neXtProt AC  NX_Q15723
Human Synonyms  EU32, NERF, NERF-1A, NERF-1a,b, NERF-1B, NERF-2
Human Chr (Location)  4q28; chr4:139057717-139177218 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(18) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Elf2 interacts with 224 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell differentiation, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleoplasm, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (314)    Tissues (204)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 305
RT-PCR 9
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(21) Primer pair(2)
Microarray probesets(5)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051593 VEGA Gene Model | MGI Sequence Detail 87944 C57BL/6J ±  kb
transcript OTTMUST00000050295 VEGA | MGI Sequence Detail 5919 Not Applicable 
polypeptide OTTMUSP00000023461 VEGA | MGI Sequence Detail 593 Not Applicable 

For the selected sequences
All sequences(112) RefSeq(18) UniProt(12)
Polymorphisms
SNPs within 2kb(605 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000418 Ets domain
InterPro IPR022084 Transcription factor Elf, N-terminal
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007021 ETS-related transcription factor Elf-2
References
(Earliest) J:115181 Wilkinson DA, et al., Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia. Leukemia. 1997 Jan;11(1):86-96
(Latest) J:179397 Schachterle W, et al., ETS-dependent regulation of a distal Gata4 cardiac enhancer. Dev Biol. 2012 Jan 15;361(2):439-49
All references(48)
Other
accession IDs
MGI:2139969, MGI:2140032

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory