Pdzph1 Gene Detail

Summary

• Symbol
  Pdzph1
• Name
  PDZ and pleckstrin homology domains 1
• Synonyms
  2610034M16Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1916489
  NCBI Gene: 69239
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr17:58878808-58991375 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    112568 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 30.57 cM, cytoband E1.1
• Mapping Data
  3 experiments

Homology

• Human Ortholog
  PDZPH1P, PDZ and pleckstrin homology domains 1, pseudogene

• Vertebrate Orthologs
  4

• Human Ortholog
  PDZPH1P, PDZ and pleckstrin homology domains 1, pseudogene
  Orthology source: HGNC
• Links
  HGNC:51488

  NCBI Gene ID: 105379197

  
  
• Chr Location
  chr5:103430533-103526618 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 130756
  1 mouse;1 cattle;1 dog;1 chicken
  
• HCOP
  human homology predictions: PDZPH1P
• Gene Tree
  Pdzph1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  4
• Gene trapped
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  4 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• cDNA Data
  19

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• Pdzph1 interacts with 107 markers (Mir19b-1, Mir19b-2, Mir22, ...) View All

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  5
• CCDS
  CCDS37673.1
• UniGene
  246732

• VEGA
  OTTMUSG00000033584 (Evidence)
• Ensembl
  ENSMUSG00000024227 (Evidence)
• NCBI Gene
  69239

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000033584	VEGA Gene Model | MGI Sequence Detail	112568	C57BL/6J
transcript	OTTMUST00000084595	VEGA | MGI Sequence Detail	4174	Not Applicable
polypeptide	OTTMUSP00000045613	VEGA | MGI Sequence Detail	1238	Not Applicable

Polymorphisms

• SNPs within 2kb
  662 from dbSNP Build 142

Protein
Information

• UniProt
  5 Sequences
• InterPro Domains
  IPR001478 PDZ domain
  IPR036034 PDZ superfamily
  IPR011993 PH-like domain superfamily
  IPR001849 Pleckstrin homology domain

Molecular
Reagents

• All nucleic 20

  cDNA 19

  Primer pair 1

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2147022

References

• Summaries
  All 22

  Phenotypes 3
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42