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Gtpbp4 Gene Detail
Summary
  • Symbol
    Gtpbp4
  • Name
    GTP binding protein 4
  • Synonyms
    2610028C09Rik, Crfg, Nog1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916487
    NCBI Gene: 69237
  • Gene Overview
    MyGene.info: GTPBP4
Location & Maps
more
  • Sequence Map
    Chr13:8972464-8996012 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23549 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 3.64 cM, cytoband A1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GTPBP4, GTP binding protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GTPBP4, GTP binding protein 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CRFG, NGB, NOG1
  • Links
    NCBI Gene ID: 23560
    neXtProt AC: NX_Q9BZE4

  • Chr Location
    10p15-p14; chr10:988409-1017768 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7100
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: GTPBP4
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69237 NCBI Gene Model | MGI Sequence Detail 23549 C57BL/6J ±  kb
transcript NM_027000 RefSeq | MGI Sequence Detail 2579 C57BL/6  
polypeptide Q99ME9 UniProt | EBI | MGI Sequence Detail 634 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    245 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000008336 nucleolar GTP-binding protein 1
  • InterPro Domains
    IPR006073 GTP binding domain
    IPR012973 NOG, C-terminal
    IPR024926 Nucleolar GTP-binding protein 1
    IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain
    IPR031167 OBG-type guanine nucleotide-binding (G) domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:1927543
References
more
  • Summaries
    All 32
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218306 Wang M, et al., Two orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesis. Nucleic Acids Res. 2014;42(17):11180-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory