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Gtpbp4 Gene Detail
Summary
  • Symbol
    Gtpbp4
  • Name
    GTP binding protein 4
  • Synonyms
    2610028C09Rik, Crfg, Nog1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916487
    NCBI Gene: 69237
  • Gene Overview
    MyGene.info: GTPBP4
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:8972070-8996532 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 3.64 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    249 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916487
protein coding gene Chr13:8966331-8996532 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020222
protein coding gene Chr13:5595307-5619250 (-)
A/J MGP_AJ_G0020178
protein coding gene Chr13:5592103-5616299 (-)
AKR/J MGP_AKRJ_G0020153
protein coding gene Chr13:5649897-5674173 (-)
BALB/cJ MGP_BALBcJ_G0020161
protein coding gene Chr13:5590303-5614482 (-)
C3H/HeJ MGP_C3HHeJ_G0019965
protein coding gene Chr13:5778004-5802871 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020608
protein coding gene Chr13:5955267-5980201 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018215
protein coding gene Chr13:5530164-5554559 (-)
CAST/EiJ MGP_CASTEiJ_G0019503
protein coding gene Chr13:5488390-5514180 (-)
CBA/J MGP_CBAJ_G0019932
protein coding gene Chr13:6075152-6109285 (-)
DBA/2J MGP_DBA2J_G0020049
protein coding gene Chr13:5422596-5447973 (-)
FVB/NJ MGP_FVBNJ_G0020034
protein coding gene Chr13:5278447-5304424 (-)
LP/J MGP_LPJ_G0020123
protein coding gene Chr13:5701956-5726098 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020070
protein coding gene Chr13:6404516-6428864 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020636
protein coding gene Chr13:5603623-5627655 (-)
PWK/PhJ MGP_PWKPhJ_G0019266
protein coding gene Chr13:5441586-5469658 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019073
protein coding gene Chr13:5605394-5633936 (-)
WSB/EiJ MGP_WSBEiJ_G0019563
protein coding gene Chr13:5511454-5538269 (-)



Homology
more
  • Human Ortholog
    GTPBP4, GTP binding protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GTPBP4, GTP binding protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CRFG, NGB, NOG1
  • Links
    NCBI Gene ID: 23560
    neXtProt AC: NX_Q9BZE4
    UniProt: Q9BZE4

  • Chr Location
    10p15.3; chr10:988409-1017768 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7100
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GTPBP4
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69237 NCBI Gene Model | MGI Sequence Detail 24463 C57BL/6J ±  kb
transcript NM_027000 RefSeq | MGI Sequence Detail 2579 C57BL/6  
polypeptide Q99ME9 UniProt | EBI | MGI Sequence Detail 634 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
less
MGI:1927543
References
more
  • Summaries
    All 34
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:64988 Burmester T, et al., A vertebrate globin expressed in the brain. Nature. 2000 Sep 28;407(6803):520-3
  • Latest
    J:218306 Wang M, et al., Two orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesis. Nucleic Acids Res. 2014;42(17):11180-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory