About   Help   FAQ
Srsf11 Gene Detail
Summary
  • Symbol
    Srsf11
  • Name
    serine/arginine-rich splicing factor 11
  • Synonyms
    0610009J05Rik, 2610019N13Rik, Sfrs11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916457
    NCBI Gene: 69207
  • Gene Overview
    MyGene.info: SRSF11
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:158010493-158036647 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 81.63 cM, cytoband H4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916457
protein coding gene Chr3:158010473-158036647 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028015
protein coding gene Chr3:162166863-162194841 (-)
A/J MGP_AJ_G0027973
protein coding gene Chr3:156258405-156284640 (-)
AKR/J MGP_AKRJ_G0027939
protein coding gene Chr3:160407295-160434646 (-)
BALB/cJ MGP_BALBcJ_G0027985
protein coding gene Chr3:156071846-156098006 (-)
C3H/HeJ MGP_C3HHeJ_G0027715
protein coding gene Chr3:160807439-160833679 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028428
protein coding gene Chr3:167485114-167511592 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025767
protein coding gene Chr3:150868684-150894612 (-)
CAST/EiJ MGP_CASTEiJ_G0027168
protein coding gene Chr3:160950353-160979889 (-)
CBA/J MGP_CBAJ_G0027690
protein coding gene Chr3:173429594-173458085 (-)
DBA/2J MGP_DBA2J_G0027830
protein coding gene Chr3:155306200-155332415 (-)
FVB/NJ MGP_FVBNJ_G0027797
protein coding gene Chr3:152656677-152682811 (-)
LP/J MGP_LPJ_G0027941
protein coding gene Chr3:163495971-163525685 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027830
protein coding gene Chr3:182016454-182043179 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028487
protein coding gene Chr3:160087030-160113210 (-)
PWK/PhJ MGP_PWKPhJ_G0026891
protein coding gene Chr3:155234199-155261495 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026719
protein coding gene Chr3:158301321-158327464 (-)
WSB/EiJ MGP_WSBEiJ_G0027248
protein coding gene Chr3:161050861-161077497 (-)



Homology
more
  • Human Ortholog
    SRSF11, serine and arginine rich splicing factor 11
  • Vertebrate Orthologs
    5
  • Human Ortholog
    SRSF11, serine and arginine rich splicing factor 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    dJ677H15.2, NET2, p54, SFRS11
  • Links
    NCBI Gene ID: 9295
    neXtProt AC: NX_Q05519
    UniProt: Q05519

  • Chr Location
    1p31.1; chr1:70205682-70252020 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69207 NCBI Gene Model | MGI Sequence Detail 26155 C57BL/6J ±  kb
transcript NM_001356997 RefSeq | MGI Sequence Detail 4159 C57BL/6  
polypeptide NP_001087221 RefSeq | MGI Sequence Detail 511 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    19 Sequences
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
    IPR034447 Serine/arginine-rich splicing factor 11
Molecular
Reagents
less
  • All nucleic 28
    cDNA 26
    Primer pair 1
    Other 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1921339, MGI:2683641
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:256883 Zhou J, et al., Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/11/2018
MGI 6.13
The Jackson Laboratory