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Dhx16 Gene Detail
Summary
  • Symbol
    Dhx16
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 16
  • Synonyms
    2410006N22Rik, DBP2, Ddx16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916442
    NCBI Gene: 69192
  • Gene Overview
    MyGene.info: DHX16
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35879819-35892670 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.74 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916442
protein coding gene Chr17:35879764-35892670 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023658
protein coding gene Chr17:36084569-36098312 (+)
A/J MGP_AJ_G0023613
protein coding gene Chr17:34960807-34974853 (+)
AKR/J MGP_AKRJ_G0023583
protein coding gene Chr17:35396718-35411632 (+)
BALB/cJ MGP_BALBcJ_G0023618
protein coding gene Chr17:35106833-35122402 (+)
C3H/HeJ MGP_C3HHeJ_G0023384
protein coding gene Chr17:35856480-35870866 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024060
protein coding gene Chr17:37551856-37566531 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021538
protein coding gene Chr17:32657229-32668652 (+)
CAST/EiJ MGP_CASTEiJ_G0022875
protein coding gene Chr17:35965356-35982657 (+)
CBA/J MGP_CBAJ_G0023362
protein coding gene Chr17:39135078-39149533 (+)
DBA/2J MGP_DBA2J_G0023486
protein coding gene Chr17:34266619-34280530 (+)
FVB/NJ MGP_FVBNJ_G0023457
protein coding gene Chr17:34061848-34075993 (+)
LP/J MGP_LPJ_G0023566
protein coding gene Chr17:36464494-36484358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023478
protein coding gene Chr17:37910669-37924174 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024103
protein coding gene Chr17:35704095-35720261 (+)
PWK/PhJ MGP_PWKPhJ_G0022626
protein coding gene Chr17:33127764-33139543 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022445
protein coding gene Chr17:33754774-33767895 (+)
WSB/EiJ MGP_WSBEiJ_G0022941
protein coding gene Chr17:35853151-35867703 (+)



Homology
more
  • Human Ortholog
    DHX16, DEAH-box helicase 16
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DHX16, DEAH-box helicase 16
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DBP2, DDX16, PRO2014, Prp2, PRP8, PRPF2
  • Links
    NCBI Gene ID: 8449
    neXtProt AC: NX_O60231
    UniProt: O60231

  • Chr Location
    6p21.33; chr6:30653119-30673053 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024422 Ensembl Gene Model | MGI Sequence Detail 12852 C57BL/6J ±  kb
transcript ENSMUST00000025292 Ensembl | MGI Sequence Detail 3351 Not Applicable  
polypeptide ENSMUSP00000025292 Ensembl | MGI Sequence Detail 1044 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR011545 DEAD/DEAH box helicase domain
    IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 85
    cDNA 85

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory