Cnppd1 MGI Mouse Gene Detail - MGI:1916421 - cyclin Pas1/PHO80 domain containing 1

Symbol

Cnppd1
Name

cyclin Pas1/PHO80 domain containing 1
Synonyms

1810031K17Rik

Feature Type

protein coding gene
IDs

MGI:1916421
NCBI Gene: 69171
Alliance

gene page
Transcription Start Sites

13 TSS

Sequence Map

Chr1:75112406-75119374 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 38.60 cM
Mapping Data

2 experiments

SNPs within 2kb

10 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916421	protein coding gene	Chr1:75111198-75119374 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0016171	protein coding gene	Chr1:75693138-75703623 (-)
A/J	MGP_AJ_G0016154	protein coding gene	Chr1:73055360-73063497 (-)
AKR/J	MGP_AKRJ_G0016111	protein coding gene	Chr1:75083836-75091985 (-)
BALB/cJ	MGP_BALBcJ_G0016109	protein coding gene	Chr1:73118572-73126731 (-)
C3H/HeJ	MGP_C3HHeJ_G0015940	protein coding gene	Chr1:75415159-75423313 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0016562	protein coding gene	Chr1:78647345-78655504 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014283	protein coding gene	Chr1:68618188-68626467 (-)
CAST/EiJ	MGP_CASTEiJ_G0015524	protein coding gene	Chr1:74751807-74760113 (-)
CBA/J	MGP_CBAJ_G0015913	protein coding gene	Chr1:81200889-81209042 (-)
DBA/2J	MGP_DBA2J_G0016014	protein coding gene	Chr1:72375225-72383384 (-)
FVB/NJ	MGP_FVBNJ_G0016017	protein coding gene	Chr1:71571654-71579815 (-)
LP/J	MGP_LPJ_G0016086	protein coding gene	Chr1:76819302-76827457 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016037	protein coding gene	Chr1:84562015-84570161 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016609	protein coding gene	Chr1:75152222-75160381 (-)
PWK/PhJ	MGP_PWKPhJ_G0015311	protein coding gene	Chr1:71843214-71851632 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0015089	protein coding gene	Chr1:74514826-74522647 (-)
WSB/EiJ	MGP_WSBEiJ_G0015586	protein coding gene	Chr1:74965646-74973787 (-)

Human Ortholog

CNPPD1, cyclin Pas1/PHO80 domain containing 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CNPPD1, cyclin Pas1/PHO80 domain containing 1
Synonyms

C2orf24, CGI-57
Links

HGNC:25220

NCBI Gene ID: 27013

neXtProt AC: NX_Q9BV87

UniProt: Q9BV87
Chr Location

2q35; chr2:219171897-219178156 (-) GRCh38

MGI Vertebrate Homology

Cnppd1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CNPPD1
Gene Tree

Cnppd1

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References

1 with disease annotations

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
23 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

1
Radiation induced

2
Spontaneous

1
Targeted

2
Genomic Mutations

4 involving Cnppd1
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

11 strains or lines available

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All GO Annotations

5
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

782
Tissues

45
cDNA Data

102
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase cnppd1

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All Sequences

81
RefSeq

8
UniProt

7
CCDS

CCDS15063.1

Ensembl

ENSMUSG00000033159 (Evidence)
NCBI Gene

69171

			Length	Strain/Species	Flank
genomic	69171	NCBI Gene Model \| MGI Sequence Detail	6969	C57BL/6J	± kb
transcript	NM_026977	RefSeq \| MGI Sequence Detail	2469	C57BL/6
polypeptide	Q8K158	UniProt \| EBI \| MGI Sequence Detail	407	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000029099 protein CNPPD1

(term hierarchy)
InterPro Domains

IPR036915 Cyclin-like superfamily

IPR013922 Cyclin PHO80-like

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All nucleic 102

cDNA 102

Microarray probesets 4

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MGI:2138501

Summaries

All 50

Developmental Gene Expression 4

Diseases 1

Gene Ontology 3

Phenotypes 23
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:260073 Will AJ, et al., Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog). Nat Genet. 2017 Oct;49(10):1539-1545

TSS for Cnppd1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr12359	Chr1:75119278-75119369 (-)	50 bp
Tssr12358	Chr1:75119004-75119068 (-)	338 bp
Tssr12357	Chr1:75118968-75118998 (-)	391 bp
Tssr12356	Chr1:75118436-75118447 (-)	932 bp
Tssr12355	Chr1:75118373-75118387 (-)	994 bp
Tssr12354	Chr1:75118270-75118292 (-)	1,093 bp
Tssr12353	Chr1:75118216-75118250 (-)	1,141 bp
Tssr12352	Chr1:75118175-75118188 (-)	1,192 bp
Tssr12351	Chr1:75118162-75118174 (-)	1,206 bp
Tssr12350	Chr1:75118153-75118159 (-)	1,218 bp
Tssr12349	Chr1:75116040-75116044 (-)	3,332 bp
Tssr12348	Chr1:75114048-75114068 (-)	5,316 bp
Tssr12347	Chr1:75113232-75113245 (-)	6,135 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23