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Fcmr
Gene Detail
Symbol

Name
ID
Fcmr
Fc fragment of IgM receptor
MGI:1916419
Synonyms
1810037B05Rik, Faim3, FcmuR
Feature Type
protein coding gene
Genetic Map
Chromosome 1
56.89 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:130865669-130880791 bp, + strand
From VEGA annotation of GRCm38

  15123 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48347  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: FCMR
Gene Tree: Fcmr

Human
homologs
FCMR, Fc fragment of IgM receptor
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9214
neXtProt AC: NX_O60667

Human Synonyms: FAIM3, TOSO

Human Chr (Location): 1q32.1; chr1:206903285-206922033 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from APF )
 
Mice homozygous for knock-out alleles exhibit a slight decrease in B cell numbers reduced sensitivity to Gal-induced liver damage, increased granulocyte production of ROS and increased sensitivity to infection by Listeria monocytogenes.
 
Interactions
Fcmr interacts with 16 markers (Mir30b, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process immune system process
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
cDNA source data(18)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026802 (Evidence)
Ensembl Gene Model ENSMUSG00000042474 (Evidence)
Entrez Gene 69169 (Evidence)
UniGene 46042
DFCI TC1680504
DoTS DT.99839321
NIA Mouse Gene Index U000776
Consensus CDS Project CCDS15261.1
International Mouse Phenotyping Consortium Status Fcmr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026802 VEGA Gene Model | MGI Sequence Detail 15123 C57BL/6J ±  kb
transcript OTTMUST00000066278 VEGA | MGI Sequence Detail 1600 Not Applicable 
polypeptide OTTMUSP00000033196 VEGA | MGI Sequence Detail 422 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000007329 Fas apoptotic inhibitory molecule 3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:220222 Kubagawa H, et al., Nomenclature of Toso, Fas Apoptosis Inhibitory Molecule 3, and IgM FcR. J Immunol. 2015 May 1;194(9):4055-7
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory