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Faim3
Gene Detail
 Symbol
Name
ID
Faim3
Fas apoptotic inhibitory molecule 3
MGI:1916419
Synonyms 1810037B05Rik, FcmuR
Feature Type protein coding gene
Genetic Map
Chromosome 1
56.89 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:130865669-130880791 bp, + strand
From VEGA annotation of GRCm38

  15123 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48347  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Faim3

Human
homologs
Human Homolog FAIM3, Fas apoptotic inhibitory molecule 3
NCBI Gene ID 9214
neXtProt AC  NX_O60667
Human Synonyms  FCMR, TOSO
Human Chr (Location)  1q32.1; chr1:206903285-206922033 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from APF )
 
Mice homozygous for knock-out alleles exhibit a slight decrease in B cell numbers reduced sensitivity to Gal-induced liver damage, increased granulocyte production of ROS and increased sensitivity to infection by Listeria monocytogenes.
 
Interactions
Faim3 interacts with 16 markers (Mir30b, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process immune system process
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026802 (Evidence)
Ensembl Gene ModelENSMUSG00000042474 (Evidence)
Entrez Gene69169 (Evidence)
UniGene46042
DFCITC1680504
DoTSDT.99839321
NIA Mouse Gene IndexU000776
Consensus CDS ProjectCCDS15261.1
International Mouse Knockout Project StatusFaim3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026802 VEGA Gene Model | MGI Sequence Detail 15123 C57BL/6J ±  kb
transcript OTTMUST00000066278 VEGA | MGI Sequence Detail 1600 Not Applicable 
polypeptide OTTMUSP00000033196 VEGA | MGI Sequence Detail 422 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000007329 Fas apoptotic inhibitory molecule 3
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206465 Brenner D, et al., Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1060-5
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory