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Ppp1r12b Gene Detail
Summary
  • Symbol
    Ppp1r12b
  • Name
    protein phosphatase 1, regulatory subunit 12B
  • Synonyms
    1810037O03Rik, 9530009M10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916417
    NCBI Gene: 329251
  • Gene Overview
    MyGene.info: PPP1R12B
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:134754658-134955942 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 58.24 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2061 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916417
protein coding gene Chr1:134754658-134955965 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016513
protein coding gene Chr1:138458174-138679525 (-)
A/J MGP_AJ_G0016496
protein coding gene Chr1:133233363-133441318 (-)
AKR/J MGP_AKRJ_G0016461
protein coding gene Chr1:137210726-137420449 (-)
BALB/cJ MGP_BALBcJ_G0016456
protein coding gene Chr1:133555656-133760150 (-)
C3H/HeJ MGP_C3HHeJ_G0016282
protein coding gene Chr1:137299733-137511651 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016917
protein coding gene Chr1:143484934-143703952 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014628
protein coding gene Chr1:126354680-126557454 (-)
CAST/EiJ MGP_CASTEiJ_G0015862
protein coding gene Chr1:136362215-136582985 (-)
CBA/J MGP_CBAJ_G0016255
protein coding gene Chr1:148430247-148653075 (-)
DBA/2J MGP_DBA2J_G0016361
protein coding gene Chr1:132237669-132447023 (-)
FVB/NJ MGP_FVBNJ_G0016360
protein coding gene Chr1:130875975-131082741 (-)
LP/J MGP_LPJ_G0016432
protein coding gene Chr1:139714665-139925367 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016385
protein coding gene Chr1:154131816-154356816 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016953
protein coding gene Chr1:136944833-137158959 (-)
PWK/PhJ MGP_PWKPhJ_G0015648
protein coding gene Chr1:131260872-131468789 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015435
protein coding gene Chr1:135908382-136126984 (-)
WSB/EiJ MGP_WSBEiJ_G0015925
protein coding gene Chr1:136971828-137188141 (-)



Homology
more
  • Human Ortholog
    PPP1R12B, protein phosphatase 1 regulatory subunit 12B
  • Vertebrate Orthologs
    3
  • Human Ortholog
    PPP1R12B, protein phosphatase 1 regulatory subunit 12B
    Orthology source: HGNC
  • Synonyms
    MYPT2, PP1bp55
  • Links
    NCBI Gene ID: 4660
    neXtProt AC: NX_O60237
    UniProt: O60237

  • Chr Location
    1q32.1; chr1:202348702-202588569 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073557 Ensembl Gene Model | MGI Sequence Detail 201285 C57BL/6J ±  kb
transcript ENSMUST00000086444 Ensembl | MGI Sequence Detail 3137 Not Applicable  
polypeptide ENSMUSP00000083633 Ensembl | MGI Sequence Detail 992 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR036770 Ankyrin repeat-containing domain superfamily
    IPR031775 cGMP-dependent protein kinase, interacting domain
    IPR017401 Protein phosphatase 1 regulatory subunit 12A/B/C
Molecular
Reagents
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  • All nucleic 16
    Genomic 1
    cDNA 15

    Microarray probesets 11
Other
Accession IDs
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MGI:2138164, MGI:2444883
References
more
  • Summaries
    All 37
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory