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Ppp1r12b Gene Detail
Summary
  • Symbol
    Ppp1r12b
  • Name
    protein phosphatase 1, regulatory (inhibitor) subunit 12B
  • Synonyms
    1810037O03Rik, 9530009M10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916417
    NCBI Gene: 329251
  • Gene Overview
    MyGene.info: PPP1R12B
Location & Maps
more
  • Sequence Map
    Chr1:134754658-134955942 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      201285 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 58.24 cM, cytoband F
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PPP1R12B, protein phosphatase 1 regulatory subunit 12B
  • Vertebrate Orthologs
    3
  • Human Ortholog
    PPP1R12B, protein phosphatase 1 regulatory subunit 12B
    Orthology source: HGNC
  • Synonyms
    MYPT2, PP1bp55
  • Links
    NCBI Gene ID: 4660
    neXtProt AC: NX_O60237

  • Chr Location
    1q32.1; chr1:202348702-202588569 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    2
  • Gene trapped
    11
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Ppp1r12b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021600 VEGA Gene Model | MGI Sequence Detail 201285 C57BL/6J ±  kb
transcript OTTMUST00000051282 VEGA | MGI Sequence Detail 8840 Not Applicable  
polypeptide OTTMUSP00000024096 VEGA | MGI Sequence Detail 976 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2061 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013108 protein phosphatase 1 regulatory subunit 12B
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR031775 cGMP-dependent protein kinase, interacting domain
    IPR017401 Protein phosphatase 1 regulatory subunit 12A/B, chordates
Molecular
Reagents
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  • All nucleic 15
    cDNA 15

    Microarray probesets 11
Other
Accession IDs
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MGI:2138164, MGI:2444883
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory