About   Help   FAQ
Cd209b
Gene Detail
 Symbol
Name
ID
Cd209b
CD209b antigen
MGI:1916415
Synonyms 1810030I22Rik, mSIGNR1, SIGNR1
Feature Type protein coding gene
Genetic Map
Chromosome 8
1.92 cM, cytoband A1.2-A1.3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr8:3917657-3926814 bp, - strand
From NCBI annotation of GRCm38

  9158 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84858  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Gene Tree: Cd209b

Alleles
and
phenotypes
All alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Homozygous mutants are more susceptible to S. pneumoniae infection and fail to clear the bacteria from the circulation. Marginal zone and peritoneal macrophages are impaired in recognizing the bacteria.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process detection of bacterium, detection of yeast, ...
Component external side of plasma membrane, integral component of membrane, ...
Function (1->3)-beta-D-glucan binding, carbohydrate binding, ...
External Resources: FuncBase
Expression
cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(18) Genomic(1) cDNA(15) Other(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000065987 (Evidence)
Entrez Gene69165 (Evidence)
UniGene175163
DFCITC1583834, TC1594382
DoTSDT.101291976, DT.97388549, DT.99773330, DT.99773355
NIA Mouse Gene IndexU102797
PDB3ZHG
Consensus CDS ProjectCCDS22076.1, CCDS22077.1, CCDS72089.1
International Mouse Knockout Project StatusCd209b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 69165 NCBI Gene Model | MGI Sequence Detail 9158 C57BL/6J ±  kb
transcript NM_026972 RefSeq | MGI Sequence Detail 2068 C57BL/6 
polypeptide Q8CJ91 UniProt | EBI | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000006172 CD209 molecule-like protein B
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:209808 Yano J, et al., Vaginal epithelial cell-derived S100 alarmins induced by Candida albicans via pattern recognition receptor interactions are sufficient but not necessary for the acute neutrophil response during experimental vaginal candidiasis. Infect Immun. 2014 Feb;82(2):783-92
All references(48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory