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Cd209b
Gene Detail
Symbol

Name
ID
Cd209b
CD209b antigen
MGI:1916415
Synonyms
1810030I22Rik, mSIGNR1, SIGNR1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
1.92 cM, cytoband A1.2-A1.3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr8:3917655-3926844 bp, - strand
From VEGA annotation of GRCm38

  9190 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84858  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Gene Tree: Cd209b

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF , CvDC )
 
Homozygous mutants are more susceptible to S. pneumoniae infection and fail to clear the bacteria from the circulation. Marginal zone and peritoneal macrophages are impaired in recognizing the bacteria.
 
Interactions
Cd209b interacts with 154 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process detection of bacterium, detection of yeast, ...
Component external side of plasma membrane, integral component of membrane, ...
Function (1->3)-beta-D-glucan binding, carbohydrate binding, ...
External Resources: FuncBase
Expression
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) Genomic(1) cDNA(15) Other(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000049043 (Evidence)
Ensembl Gene Model ENSMUSG00000065987 (Evidence)
Entrez Gene 69165 (Evidence)
UniGene 175163
DFCI TC1583834, TC1594382
DoTS DT.101291976, DT.97388549, DT.99773330, DT.99773355
NIA Mouse Gene Index U102797
PDB 3ZHG, 4C9F, 4CAJ
Consensus CDS Project CCDS22076.1, CCDS22077.1, CCDS72089.1
International Mouse Phenotyping Consortium Status Cd209b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049043 VEGA Gene Model | MGI Sequence Detail 9190 C57BL/6J ±  kb
transcript OTTMUST00000125268 VEGA | MGI Sequence Detail 2039 Not Applicable 
polypeptide OTTMUSP00000067958 VEGA | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(10) UniProt(3)
Polymorphisms
SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000006172 CD209 molecule-like protein B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:221177 Fiebiger BM, et al., Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs. Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2385-94
All references(52)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory