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Sec31a Gene Detail
Summary
  • Symbol
    Sec31a
  • Name
    Sec31 homolog A (S. cerevisiae)
  • Synonyms
    1810024J13Rik, Sec31l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916412
    NCBI Gene: 69162
  • Gene Overview
    MyGene.info: SEC31A
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:100361649-100416234 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 48.48 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916412
protein coding gene Chr5:100361649-100416255 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029785
protein coding gene Chr5:101841027-101897032 (-)
A/J MGP_AJ_G0029751
protein coding gene Chr5:98051866-98106436 (-)
AKR/J MGP_AKRJ_G0029697
protein coding gene Chr5:101283763-101338331 (-)
BALB/cJ MGP_BALBcJ_G0029761
protein coding gene Chr5:99080557-99135857 (-)
C3H/HeJ MGP_C3HHeJ_G0029484
protein coding gene Chr5:101633254-101688265 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030216
protein coding gene Chr5:106075392-106129969 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027451
protein coding gene Chr5:93286451-93343145 (-)
CAST/EiJ MGP_CASTEiJ_G0028895
protein coding gene Chr5:100281114-100337708 (-)
CBA/J MGP_CBAJ_G0029454
protein coding gene Chr5:109759935-109814492 (-)
DBA/2J MGP_DBA2J_G0029598
protein coding gene Chr5:98240461-98295232 (-)
FVB/NJ MGP_FVBNJ_G0029557
protein coding gene Chr5:97046117-97101014 (-)
LP/J MGP_LPJ_G0029686
protein coding gene Chr5:102457985-102512506 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029586
protein coding gene Chr5:114840309-114896032 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030249
protein coding gene Chr5:100764628-100819189 (-)
PWK/PhJ MGP_PWKPhJ_G0028613
protein coding gene Chr5:96670718-96727024 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028448
protein coding gene Chr5:98426117-98481824 (-)
WSB/EiJ MGP_WSBEiJ_G0028973
protein coding gene Chr5:101097337-101153550 (-)



Homology
more
  • Human Ortholog
    SEC31A, SEC31 homolog A, COPII coat complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC31A, SEC31 homolog A, COPII coat complex component
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ABP125, ABP130, HSPC275, HSPC334, SEC31L1
  • Links
    NCBI Gene ID: 22872
    neXtProt AC: NX_O94979
    UniProt: O94979

  • Chr Location
    4q21.22; chr4:82818509-82900571 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 42056
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SEC31A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035325 Ensembl Gene Model | MGI Sequence Detail 54586 C57BL/6J ±  kb
transcript ENSMUST00000094578 Ensembl | MGI Sequence Detail 4228 Not Applicable  
polypeptide ENSMUSP00000092157 Ensembl | MGI Sequence Detail 1230 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • InterPro Domains
    IPR024298 Ancestral coatomer element 1, Sec16/Sec31
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 178
    Genomic 2
    cDNA 176

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141084
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 14
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265909 Zhang F, et al., cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9449-E9458

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory