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Sec31a Gene Detail
Summary
  • Symbol
    Sec31a
  • Name
    Sec31 homolog A (S. cerevisiae)
  • Synonyms
    1810024J13Rik, Sec31l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916412
    NCBI Gene: 69162
  • Gene Overview
    MyGene.info: SEC31A
Location & Maps
more
  • Sequence Map
    Chr5:100361649-100416234 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      54586 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SEC31A, SEC31 homolog A, COPII coat complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC31A, SEC31 homolog A, COPII coat complex component
    Orthology source: HomoloGene
  • Synonyms
    ABP125, ABP130, HSPC275, HSPC334, SEC31L1
  • Links
    NCBI Gene ID: 22872
    neXtProt AC: NX_O94979

  • Chr Location
    4q21.22; chr4:82818661-82891280 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    45
  • Chemically induced (other)
    1
  • Gene trapped
    42
  • Radiation induced
    1
  • Spontaneous
    1
  • Genomic Mutations
    3 involving Sec31a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043627 VEGA Gene Model | MGI Sequence Detail 54586 C57BL/6J ±  kb
transcript OTTMUST00000114592 VEGA | MGI Sequence Detail 4228 Not Applicable  
polypeptide OTTMUSP00000063946 VEGA | MGI Sequence Detail 1230 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    315 from dbSNP Build 142
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000014593 protein transport protein Sec31A
  • InterPro Domains
    IPR024298 Ancestral coatomer element 1, Sec16/Sec31
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
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  • All nucleic 177
    Genomic 1
    cDNA 176

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141084
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:228212 Cinque L, et al., FGF signalling regulates bone growth through autophagy. Nature. 2015 Dec 10;528(7581):272-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory