Rhebl1
Gene Detail

Symbol Name ID

Rhebl1 Ras homolog enriched in brain like 1 MGI:1916409

Synonyms

1810036J22Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 15

54.99 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr15:98877778-98881404 bp, - strand From VEGA annotation of GRCm38   3627 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5477  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rhebl1

Human homologs

Human Homolog		RHEBL1, Ras homolog enriched in brain like 1
NCBI Gene ID		121268
neXtProt AC		NX_Q8TAI7
Human Synonyms		RHEBL1c
Human Chr (Location)		12q13.12; chr12:49458468-49463775 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(14) : Targeted(5) Gene trapped(9)
 

Mice homozygous for a null mutation are viable and fertile with no gross defects.

 

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	GTP catabolic process, positive regulation of NF-kappaB transcription factor activity, ...
Component	cytoplasm, membrane, ...
Function	GTPase activity, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (73)    Tissues (14)    Images (22)
Theiler Stages: 22, 23, 28

Assay Type	Results
RNA in situ	69
RT-PCR	4

cDNA source data(23)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000024109 (Evidence)
Ensembl Gene Model	ENSMUSG00000023755 (Evidence)
Entrez Gene	69159 (Evidence)
UniGene	259708
DFCI	TC1584548
DoTS	DT.97399282
NIA Mouse Gene Index	U036636
Consensus CDS Project	CCDS27809.1
International Mouse Knockout Project Status	Rhebl1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024109	VEGA Gene Model | MGI Sequence Detail	3627	C57BL/6J
transcript	OTTMUST00000058972	VEGA | MGI Sequence Detail	1185	Not Applicable
polypeptide	OTTMUSP00000028648	VEGA | MGI Sequence Detail	184	Not Applicable

All sequences(26) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(2 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR020849	Small GTPase superfamily, Ras type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013976	GTPase RhebL1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:168571 Zou J, et al., Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108
All references(35)