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Ifi27l2b Gene Detail
Summary
  • Symbol
    Ifi27l2b
  • Name
    interferon, alpha-inducible protein 27 like 2B
  • Synonyms
    1810023F06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916390
    NCBI Gene: 217845
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:103417157-103423482 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 52.93 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916390
 protein coding gene Chr12:103417157-103423482 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020052
 protein coding gene Chr12:105130945-105132711 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0019984
 protein coding gene Chr12:103942761-103949556 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0019796
 protein coding gene Chr12:104433943-104451632 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020443
 protein coding gene Chr12:108400618-108407265 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0019768
 protein coding gene Chr12:112437718-112448413 (-)
DBA/2J MGP_DBA2J_G0019879
 protein coding gene Chr12:100615959-100629423 (-)
FVB/NJ MGP_FVBNJ_G0019868
 protein coding gene Chr12:99347420-99365625 (-)
LP/J MGP_LPJ_G0019955
 protein coding gene Chr12:104981672-104995695 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019908
 protein coding gene Chr12:115892041-115897644 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0019396
 protein coding gene Chr12:104367100-104381003 (-)



Homology
more
  • Human Ortholog
    IFI27, interferon alpha inducible protein 27
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFI27, interferon alpha inducible protein 27
  • Synonyms
    FAM14D, ISG12, ISG12A, P27
  • Links
    NCBI Gene ID: 3429
    neXtProt AC: NX_P40305
    UniProt: P40305

  • Chr Location
    14q32.12; chr14:94104836-94116695 (+)  GRCh38
  • Human Ortholog
    IFI27L1, interferon alpha inducible protein 27 like 1
  • Synonyms
    FAM14B, ISG12C
  • Links
    NCBI Gene ID: 122509
    neXtProt AC: NX_Q96BM0
    UniProt: Q96BM0

  • Chr Location
    14q32.12; chr14:94081301-94103846 (+)  GRCh38
  • Human Ortholog
    IFI27L2, interferon alpha inducible protein 27 like 2
  • Synonyms
    FAM14A, ISG12B, TLH29
  • Links
    NCBI Gene ID: 83982
    neXtProt AC: NX_Q9H2X8
    UniProt: Q9H2X8

  • Chr Location
    14q32.12; chr14:94127779-94130253 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217845 NCBI Gene Model | MGI Sequence Detail 6326 C57BL/6J ±  kb
transcript NM_145449 RefSeq | MGI Sequence Detail 1093 C57BL/6  
polypeptide Q8VC49 UniProt | EBI | MGI Sequence Detail 283 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000033452 interferon alpha-inducible protein 27-like protein 2B
    (term hierarchy)
  • InterPro Domains
    IPR038213 IFI6/IFI27-like domain superfamily
    IPR009311 Interferon alpha-inducible protein IFI6/IFI27-like
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:186970 Lu MY, et al., Interferon-stimulated gene ISG12b2 is localized to the inner mitochondrial membrane and mediates virus-induced cell death. Cell Death Differ. 2011 Jun;18(6):925-36
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory