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Ptgr2 Gene Detail
Summary
  • Symbol
    Ptgr2
  • Name
    prostaglandin reductase 2
  • Synonyms
    1810016I24Rik, 9630002F03Rik, B830026H24Rik, PGR-2, Zadh1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916372
    NCBI Gene: 77219
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:84285237-84315832 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 39.14 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    133 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916372
protein coding gene Chr12:84285232-84315832 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019931
protein coding gene Chr12:84980649-85016967 (+)
A/J MGP_AJ_G0019888
protein coding gene Chr12:81763612-81794379 (+)
AKR/J MGP_AKRJ_G0019864
protein coding gene Chr12:83977314-84013670 (+)
BALB/cJ MGP_BALBcJ_G0019868
protein coding gene Chr12:82094819-82125672 (+)
C3H/HeJ MGP_C3HHeJ_G0019674
protein coding gene Chr12:84449069-84479093 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020319
protein coding gene Chr12:87419424-87453953 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017937
protein coding gene Chr12:78672931-78702786 (+)
CAST/EiJ MGP_CASTEiJ_G0019223
protein coding gene Chr12:79393988-79430624 (+)
CBA/J MGP_CBAJ_G0019645
protein coding gene Chr12:90797391-90834162 (+)
DBA/2J MGP_DBA2J_G0019760
protein coding gene Chr12:81298066-81328348 (+)
FVB/NJ MGP_FVBNJ_G0019746
protein coding gene Chr12:80250283-80280352 (+)
LP/J MGP_LPJ_G0019832
protein coding gene Chr12:84862900-84894759 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019785
protein coding gene Chr12:93716676-93748585 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020353
protein coding gene Chr12:83577046-83609370 (+)
PWK/PhJ MGP_PWKPhJ_G0018987
protein coding gene Chr12:75783440-75815034 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018782
protein coding gene Chr12:78063476-78095793 (+)
WSB/EiJ MGP_WSBEiJ_G0019275
protein coding gene Chr12:84290734-84320409 (+)



Homology
more
  • Human Ortholog
    PTGR2, prostaglandin reductase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PTGR2, prostaglandin reductase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HEL-S-298, PGR2, ZADH1
  • Links
    NCBI Gene ID: 145482
    neXtProt AC: NX_Q8N8N7
    UniProt: Q8N8N7

  • Chr Location
    14q24.3; chr14:73851831-73885465 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Targeted
    1
  • Genomic Mutations
    1 involving Ptgr2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 77219 NCBI Gene Model | MGI Sequence Detail 30596 C57BL/6J ±  kb
transcript NM_001252626 RefSeq | MGI Sequence Detail 3250 C57BL/6  
polypeptide Q8VDQ1 UniProt | EBI | MGI Sequence Detail 351 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 8
Other
Accession IDs
less
MGI:1924469, MGI:1926101, MGI:2144889
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:185071 Yaguchi H, et al., TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis. J Biol Chem. 2012 Apr 6;287(15):12050-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory