About   Help   FAQ
Chrdl2 Gene Detail
Summary
  • Symbol
    Chrdl2
  • Name
    chordin-like 2
  • Synonyms
    1810022C01Rik, Chl2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916371
    NCBI Gene: 69121
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:100006404-100034728 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    297 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916371
protein coding gene Chr7:100006172-100034728 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032561
protein coding gene Chr7:102860378-102888768 (+)
A/J MGP_AJ_G0032535
protein coding gene Chr7:100286045-100314404 (+)
AKR/J MGP_AKRJ_G0032471
protein coding gene Chr7:102667865-102696224 (+)
BALB/cJ MGP_BALBcJ_G0032546
protein coding gene Chr7:99955870-99984227 (+)
C3H/HeJ MGP_C3HHeJ_G0032261
protein coding gene Chr7:103036422-103065009 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033044
protein coding gene Chr7:106770525-106798822 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030038
protein coding gene Chr7:102687321-102716775 (+)
CAST/EiJ MGP_CASTEiJ_G0031588
protein coding gene Chr7:94572577-94601003 (+)
CBA/J MGP_CBAJ_G0032228
protein coding gene Chr7:110464172-110495072 (+)
DBA/2J MGP_DBA2J_G0032379
protein coding gene Chr7:98614717-98644236 (+)
FVB/NJ MGP_FVBNJ_G0032336
protein coding gene Chr7:98406223-98435538 (+)
LP/J MGP_LPJ_G0032469
protein coding gene Chr7:104220336-104249088 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032369
protein coding gene Chr7:111870341-111898700 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033066
protein coding gene Chr7:101939603-101967987 (+)
PWK/PhJ MGP_PWKPhJ_G0031306
protein coding gene Chr7:91717205-91746003 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031149
protein coding gene Chr7:89244909-89273308 (+)
WSB/EiJ MGP_WSBEiJ_G0031705
protein coding gene Chr7:102632388-102661760 (+)



Homology
more
  • Human Ortholog
    CHRDL2, chordin like 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHRDL2, chordin like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BNF1, CHL2
  • Links
    NCBI Gene ID: 25884
    neXtProt AC: NX_Q6WN34
    UniProt: Q6WN34

  • Chr Location
    11q13.4; chr11:74696428-74731385 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69121 NCBI Gene Model | MGI Sequence Detail 28325 C57BL/6J ±  kb
transcript NM_133709 RefSeq | MGI Sequence Detail 1520 C57BL/6  
polypeptide Q8VEA6 UniProt | EBI | MGI Sequence Detail 426 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001007 VWFC domain
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:236505 Souilhol C, et al., Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells. Nat Commun. 2016 Mar 08;7:10784

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory