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Chrdl2
Gene Detail
Symbol

Name
ID
Chrdl2
chordin-like 2
MGI:1916371
Synonyms
1810022C01Rik, Chl2
Feature Type
protein coding gene
Genetic Map
Chromosome 7
54.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:100006404-100034728 bp, + strand
From VEGA annotation of GRCm38

  28325 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128795  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CHRDL2
Gene Tree: Chrdl2

Human
homologs
CHRDL2, chordin-like 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 25884
neXtProt AC: NX_Q6WN34

Human Synonyms: BNF1, CHL2

Human Chr (Location): 11q14; chr11:74696428-74731385 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Chrdl2 interacts with 28 markers (Mir7-1, Mir16-2, Mir99a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cartilage development, cell differentiation, ...
Component extracellular region, extracellular space
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN chrdl2    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000024367 (Evidence)
Ensembl Gene Model ENSMUSG00000030732 (Evidence)
Entrez Gene 69121 (Evidence)
UniGene 285295
DFCI TC1587837
DoTS DT.55132057, DT.91425930
NIA Mouse Gene Index U008445
Consensus CDS Project CCDS21492.1
International Mouse Phenotyping Consortium Status Chrdl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024367 VEGA Gene Model | MGI Sequence Detail 28325 C57BL/6J ±  kb
transcript OTTMUST00000059702 VEGA | MGI Sequence Detail 1484 Not Applicable 
polypeptide OTTMUSP00000029061 VEGA | MGI Sequence Detail 433 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(301 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001007 von Willebrand factor, type C
Protein Ontology PR:000005452 chordin-like protein 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:192165 Forsman CL, et al., BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory