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Alkbh3 Gene Detail
Summary
  • Symbol
    Alkbh3
  • Name
    alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
  • Synonyms
    1700108H04Rik, 1810020C19Rik, Abh3, mABH3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916363
    NCBI Gene: 69113
Location & Maps
more
  • Sequence Map
    Chr2:93980550-94010807 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30258 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 51.62 cM, cytoband E1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ALKBH3, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ALKBH3, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ABH3, DEPC1, DEPC-1, hABH3, PCA1
  • Links
    NCBI Gene ID: 221120
    neXtProt AC: NX_Q96Q83

  • Chr Location
    11p11.2; chr11:43880807-43920275 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    14 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Alkbh3
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit a normal lifespan and are phenotypically indistinguishable from control littermates.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014996 VEGA Gene Model | MGI Sequence Detail 30258 C57BL/6J ±  kb
transcript OTTMUST00000035611 VEGA | MGI Sequence Detail 1395 Not Applicable  
polypeptide OTTMUSP00000015963 VEGA | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    220 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 55
    cDNA 55

    Microarray probesets 3
Other
Accession IDs
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MGI:1920823
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190468 Calvo JA, et al., DNA repair is indispensable for survival after acute inflammation. J Clin Invest. 2012 Jul 2;122(7):2680-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory