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Fam58b
Gene Detail
Symbol

Name
ID
Fam58b
family with sequence similarity 58, member B
MGI:1916359
Synonyms
1810009O10Rik, cyclin M
Feature Type
protein coding gene
Genetic Map
Chromosome 11
46.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:78750506-78751729 bp, - strand
From VEGA annotation of GRCm38

  1224 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13362  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Fam58b

Human
homologs
Human Homolog FAM58A, family with sequence similarity 58, member A
NCBI Gene ID 92002
neXtProt AC  NX_Q8N1B3
Human Synonyms  STAR
Human Chr (Location)  Xq28; chrX:153587925-153599177 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human FAM58A
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from APF )
Interactions
Fam58b interacts with 63 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process positive regulation of MAPK cascade, positive regulation of protein kinase activity, ...
Component cellular_component
Function protein binding, protein kinase activator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (10)    Tissues (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 10
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(23)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000000148 (Evidence)
Ensembl Gene ModelENSMUSG00000049489 (Evidence)
Entrez Gene69109 (Evidence)
UniGene341420
DFCITC1580050, TC1616702
DoTSDT.55137015
NIA Mouse Gene IndexU033140
Consensus CDS ProjectCCDS25114.1
International Mouse Knockout Project StatusFam58b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000148 VEGA Gene Model | MGI Sequence Detail 1224 C57BL/6J ±  kb
transcript OTTMUST00000000471 VEGA | MGI Sequence Detail 1224 Not Applicable 
polypeptide OTTMUSP00000000206 VEGA | MGI Sequence Detail 250 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015429 Cyclin C/H/T/L
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000029103 cyclin-related protein FAM58A
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202961 Guen VJ, et al., CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19525-30
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory