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Stoml1 Gene Detail
Summary
  • Symbol
    Stoml1
  • Name
    stomatin-like 1
  • Synonyms
    1810015E19Rik, SLP-1, UNC-24, WPB72
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916356
    NCBI Gene: 69106
  • Gene Overview
    MyGene.info: STOML1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:58253164-58262520 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 31.63 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916356
protein coding gene Chr9:58253164-58262524 (.)
129S1/SvImJ MGP_129S1SvImJ_G0034888
protein coding gene Chr9:57526723-57536865 (+)
A/J MGP_AJ_G0034869
protein coding gene Chr9:55664722-55675656 (+)
AKR/J MGP_AKRJ_G0034798
protein coding gene Chr9:56961232-56971443 (+)
BALB/cJ MGP_BALBcJ_G0034861
protein coding gene Chr9:55438649-55448299 (+)
C3H/HeJ MGP_C3HHeJ_G0034571
protein coding gene Chr9:57443907-57454065 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035380
protein coding gene Chr9:59117931-59140396 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032291
protein coding gene Chr9:54947825-54957654 (+)
CAST/EiJ MGP_CASTEiJ_G0033892
protein coding gene Chr9:57528134-57538741 (+)
CBA/J MGP_CBAJ_G0034542
protein coding gene Chr9:61212548-61221754 (+)
DBA/2J MGP_DBA2J_G0034701
protein coding gene Chr9:55519079-55528691 (+)
FVB/NJ MGP_FVBNJ_G0034643
protein coding gene Chr9:54758122-54767440 (+)
LP/J MGP_LPJ_G0034784
protein coding gene Chr9:57817284-57828924 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034686
protein coding gene Chr9:62658486-62679496 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035402
protein coding gene Chr9:56972860-56982244 (+)
PWK/PhJ MGP_PWKPhJ_G0033597
protein coding gene Chr9:55565749-55648992 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033431
protein coding gene Chr9:57257747-57276449 (+)
WSB/EiJ MGP_WSBEiJ_G0034005
protein coding gene Chr9:56910062-56933664 (+)



Homology
more
  • Human Ortholog
    STOML1, stomatin like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STOML1, stomatin like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hUNC-24, SLP-1, STORP
  • Links
    NCBI Gene ID: 9399
    neXtProt AC: NX_Q9UBI4
    UniProt: Q9UBI4

  • Chr Location
    15q24.1; chr15:73983218-73994622 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31265
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: STOML1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene-trapped allele are viable and free of overt neurological phenotypes but show a mild, but specific, disinhibition of certain proton-gated currents in dorsal root ganglia neurons.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032333 Ensembl Gene Model | MGI Sequence Detail 9357 C57BL/6J ±  kb
transcript ENSMUST00000034883 Ensembl | MGI Sequence Detail 1984 Not Applicable  
polypeptide ENSMUSP00000034883 Ensembl | MGI Sequence Detail 399 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143142
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:219161 Kozlenkov A, et al., Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1. J Physiol. 2014 Feb 15;592(Pt 4):557-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory