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Tmem160 Gene Detail
Summary
  • Symbol
    Tmem160
  • Name
    transmembrane protein 160
  • Synonyms
    1810008O21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916344
    NCBI Gene: 69094
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:16186867-16189415 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.13 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916344
 protein coding gene Chr7:16186704-16189419 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031710
 protein coding gene Chr7:14165167-14167883 (+)
A/J MGP_AJ_G0031682
 protein coding gene Chr7:13925969-13928679 (+)
AKR/J MGP_AKRJ_G0031607
 protein coding gene Chr7:14246780-14249489 (+)
BALB/cJ MGP_BALBcJ_G0031689
 protein coding gene Chr7:14032966-14035676 (+)
C3H/HeJ MGP_C3HHeJ_G0031411
 protein coding gene Chr7:14433859-14436575 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032155
 protein coding gene Chr7:14912329-14915039 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029234
 protein coding gene Chr7:15474307-15477077 (+)
CAST/EiJ MGP_CASTEiJ_G0030762
 protein coding gene Chr7:11195058-11197875 (+)
CBA/J MGP_CBAJ_G0031370
 protein coding gene Chr7:15378836-15381552 (+)
DBA/2J MGP_DBA2J_G0031526
 protein coding gene Chr7:13811028-13813744 (+)
FVB/NJ MGP_FVBNJ_G0031482
 protein coding gene Chr7:13711185-13713895 (+)
LP/J MGP_LPJ_G0031611
 protein coding gene Chr7:14411265-14413981 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031517
 protein coding gene Chr7:15327891-15330601 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032184
 protein coding gene Chr7:14024543-14027252 (+)
PWK/PhJ MGP_PWKPhJ_G0030486
 protein coding gene Chr7:11335558-11338274 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030313
 protein coding gene Chr7:8938729-8941447 (+)
WSB/EiJ MGP_WSBEiJ_G0030859
 protein coding gene Chr7:14082987-14085696 (+)



Homology
more
  • Human Ortholog
    TMEM160, transmembrane protein 160
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM160, transmembrane protein 160
  • Links
    NCBI Gene ID: 54958
    neXtProt AC: NX_Q9NX00
    UniProt: Q9NX00

  • Chr Location
    19q13.32; chr19:47045909-47048624 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 3 alleles in 3 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for null allele display altered pain related behaviors and altered cytokine profiles in the dorsal root ganglion.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    38
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69094 NCBI Gene Model | MGI Sequence Detail 2549 C57BL/6J ±  kb
    transcript NR_184858 RefSeq | MGI Sequence Detail 716 C57BL/6  
    polypeptide Q9D938 UniProt | EBI | MGI Sequence Detail 188 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 38
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:328221 Segelcke D, et al., Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice. Cell Rep. 2021 Dec 21;37(12):110152
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory