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Sgsm3 Gene Detail
Summary
  • Symbol
    Sgsm3
  • Name
    small G protein signaling modulator 3
  • Synonyms
    1810012I01Rik, CIP85, Rutbc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916329
    NCBI Gene: 105835
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:80977765-81012290 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    113 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916329
 protein coding gene Chr15:80977765-81012290 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022105
 protein coding gene Chr15:81370005-81413701 (+)
A/J MGP_AJ_G0022066
 protein coding gene Chr15:78525051-78558990 (+)
AKR/J MGP_AKRJ_G0022041
 protein coding gene Chr15:80718202-80751922 (+)
BALB/cJ MGP_BALBcJ_G0022072
 protein coding gene Chr15:78530065-78569612 (+)
C3H/HeJ MGP_C3HHeJ_G0021843
 protein coding gene Chr15:80704444-80740784 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022515
 protein coding gene Chr15:84555938-84595922 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020045
 protein coding gene Chr15:75001124-75035447 (+)
CAST/EiJ MGP_CASTEiJ_G0021364
 protein coding gene Chr15:81453335-81489794 (+)
CBA/J MGP_CBAJ_G0021808
 protein coding gene Chr15:87205597-87251557 (+)
DBA/2J MGP_DBA2J_G0021937
 protein coding gene Chr15:78014223-78048937 (+)
FVB/NJ MGP_FVBNJ_G0021915
 protein coding gene Chr15:77050631-77085124 (+)
LP/J MGP_LPJ_G0022005
 protein coding gene Chr15:81534951-81571706 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021935
 protein coding gene Chr15:92194733-92234014 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022529
 protein coding gene Chr15:80766149-80804114 (+)
PWK/PhJ MGP_PWKPhJ_G0021106
 protein coding gene Chr15:78031093-78068737 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020943
 protein coding gene Chr15:80561567-80596737 (+)
WSB/EiJ MGP_WSBEiJ_G0021416
 protein coding gene Chr15:81170532-81208859 (+)



Homology
more
  • Human Ortholog
    SGSM3, small G protein signaling modulator 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SGSM3, small G protein signaling modulator 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CIP85, MAP, RabGAP-5, RABGAP5, rabGAPLP, RUSC3, RUTBC3
  • Links
    NCBI Gene ID: 27352
    neXtProt AC: NX_Q96HU1
    UniProt: Q96HU1

  • Chr Location
    22q13.1; chr22:40370530-40410289 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 9249
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SGSM3
  • Gene Tree
    Sgsm3
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    109
  • Tissues
    25
  • cDNA Data
    91
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105835 NCBI Gene Model | MGI Sequence Detail 34526 C57BL/6J ±  kb
transcript NM_134091 RefSeq | MGI Sequence Detail 3013 C57BL/6  
polypeptide Q8VCZ6 UniProt | EBI | MGI Sequence Detail 750 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 93
    cDNA 91
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146003, MGI:2146266, MGI:2146321
References
more
  • Summaries
    All 51
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 6
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/13/2019
MGI 6.13 		The Jackson Laboratory