About   Help   FAQ
Sgsm3 Gene Detail
Summary
  • Symbol
    Sgsm3
  • Name
    small G protein signaling modulator 3
  • Synonyms
    1810012I01Rik, CIP85, Rutbc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916329
    NCBI Gene: 105835
Location & Maps
more
  • Sequence Map
    Chr15:80977765-81012289 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      34525 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.96 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SGSM3, small G protein signaling modulator 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SGSM3, small G protein signaling modulator 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CIP85, MAP, RabGAP-5, RABGAP5, rabGAPLP, RUSC3, RUTBC3
  • Links
    NCBI Gene ID: 27352
    neXtProt AC: NX_Q96HU1
    UniProt: Q96HU1

  • Chr Location
    22q13.1; chr22:40370530-40410289 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 9249
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SGSM3
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    109
  • Tissues
    25
  • cDNA Data
    90
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034072 VEGA Gene Model | MGI Sequence Detail 34525 C57BL/6J ±  kb
transcript OTTMUST00000086075 VEGA | MGI Sequence Detail 2996 Not Applicable  
polypeptide OTTMUSP00000046552 VEGA | MGI Sequence Detail 750 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    113 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 92
    cDNA 90
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146003, MGI:2146266, MGI:2146321
References
more
  • Summaries
    All 51
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 24
  • Earliest
    J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
06/13/2017
MGI 6.10 		The Jackson Laboratory