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1810011O10Rik Gene Detail
Summary
  • Symbol
    1810011O10Rik
  • Name
    RIKEN cDNA 1810011O10 gene
  • Synonyms
    1110065B09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916318
    NCBI Gene: 69068
  • Gene Overview
    MyGene.info: C8orf4
Location & Maps
more
  • Sequence Map
    Chr8:24437180-24438984 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1805 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 12.47 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    C8orf4, chromosome 8 open reading frame 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    C8orf4, chromosome 8 open reading frame 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TC1, TC-1
  • Links
    NCBI Gene ID: 56892
    neXtProt AC: NX_Q9NR00

  • Chr Location
    8p11.2; chr8:40153468-40155308 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit myeloid and lymphoid hyperplasia, an increased number of small-sized red blood cells, increased hematopoietic stem cell number, and enhanced hematopoietic activity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045584 VEGA Gene Model | MGI Sequence Detail 1805 C57BL/6J ±  kb
transcript OTTMUST00000119458 VEGA | MGI Sequence Detail 1805 Not Applicable  
polypeptide OTTMUSP00000066450 VEGA | MGI Sequence Detail 106 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    13 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR020282 Arginine vasopressin-induced protein 1/C8orf4
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 4
Other
Accession IDs
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MGI:1915083, MGI:2142767, MGI:2142785
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:217538 Lui JH, et al., Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. Nature. 2014 Nov 13;515(7526):264-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory