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Chac1 Gene Detail
Summary
  • Symbol
    Chac1
  • Name
    ChaC, cation transport regulator 1
  • Synonyms
    1810008K03Rik, Botch
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916315
    NCBI Gene: 69065
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:119351242-119354326 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.97 cM, cytoband E5
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916315
protein coding gene Chr2:119351229-119354381 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026342
protein coding gene Chr2:122108404-122111553 (+)
A/J MGP_AJ_G0026303
protein coding gene Chr2:117126796-117129932 (+)
AKR/J MGP_AKRJ_G0026282
protein coding gene Chr2:120416094-120419245 (+)
BALB/cJ MGP_BALBcJ_G0026316
protein coding gene Chr2:117392281-117395417 (+)
C3H/HeJ MGP_C3HHeJ_G0026062
protein coding gene Chr2:120876404-120879553 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026763
protein coding gene Chr2:126123209-126126361 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024143
protein coding gene Chr2:112184773-112187858 (+)
CAST/EiJ MGP_CASTEiJ_G0025524
protein coding gene Chr2:121188630-121191780 (+)
CBA/J MGP_CBAJ_G0026038
protein coding gene Chr2:130550650-130553799 (+)
DBA/2J MGP_DBA2J_G0026177
protein coding gene Chr2:116552827-116555963 (+)
FVB/NJ MGP_FVBNJ_G0026139
protein coding gene Chr2:115374804-115377955 (+)
LP/J MGP_LPJ_G0026278
protein coding gene Chr2:122419639-122422788 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026158
protein coding gene Chr2:134898282-134901431 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026818
protein coding gene Chr2:120530922-120534071 (+)
PWK/PhJ MGP_PWKPhJ_G0025260
protein coding gene Chr2:116116135-116119387 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025059
protein coding gene Chr2:119723244-119726382 (+)
WSB/EiJ MGP_WSBEiJ_G0025593
protein coding gene Chr2:121371188-121374345 (+)



Homology
more
  • Human Ortholog
    CHAC1, ChaC glutathione specific gamma-glutamylcyclotransferase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHAC1, ChaC glutathione specific gamma-glutamylcyclotransferase 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 79094
    neXtProt AC: NX_Q9BUX1
    UniProt: Q9BUX1

  • Chr Location
    15q15.1; chr15:40942135-40956519 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11470
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CHAC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69065 NCBI Gene Model | MGI Sequence Detail 3085 C57BL/6J ±  kb
transcript NM_026929 RefSeq | MGI Sequence Detail 1583 C57BL/6  
polypeptide Q8R3J5 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005398 glutathione-specific gamma-glutamylcyclotransferase 1
  • EC
  • InterPro Domains
    IPR013024 Gamma-glutamyl cyclotransferase-like
    IPR036568 Gamma-glutamyl cyclotransferase-like superfamily
    IPR006840 Glutathione-specific gamma-glutamylcyclotransferase
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:259934 Nomura Y, et al., Translational and post-translational regulation of mouse cation transport regulator homolog 1. Sci Rep. 2016 Jun 15;6:28016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory