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Chac1 Gene Detail
Summary
  • Symbol
    Chac1
  • Name
    ChaC, cation transport regulator 1
  • Synonyms
    1810008K03Rik, Botch
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916315
    NCBI Gene: 69065
Location & Maps
more
  • Sequence Map
    Chr2:119351229-119354381 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3153 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CHAC1, ChaC glutathione-specific gamma-glutamylcyclotransferase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHAC1, ChaC glutathione-specific gamma-glutamylcyclotransferase 1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 79094
    neXtProt AC: NX_Q9BUX1

  • Chr Location
    15q15.1; chr15:40953438-40956519 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 11470
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CHAC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Chac1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015948 VEGA Gene Model | MGI Sequence Detail 3153 C57BL/6J ±  kb
transcript OTTMUST00000037907 VEGA | MGI Sequence Detail 1637 Not Applicable  
polypeptide OTTMUSP00000017015 VEGA | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    65 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005398 cation transport regulator-like protein 1
  • EC
  • InterPro Domains
    IPR013024 Butirosin biosynthesis, BtrG-like
    IPR006840 ChaC-like protein
Molecular
Reagents
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  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:184017 Chi Z, et al., Botch promotes neurogenesis by antagonizing Notch. Dev Cell. 2012 Apr 17;22(4):707-20

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory