Chac1
Gene Detail

Symbol Name ID

Chac1 ChaC, cation transport regulator 1 MGI:1916315

Synonyms

1810008K03Rik, Botch

Feature Type

protein coding gene

Genetic Map

Chromosome 2

59.97 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr2:119351229-119354381 bp, + strand From VEGA annotation of GRCm38   3153 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:11470  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Chac1

Human homologs

Human Homolog		CHAC1, ChaC, cation transport regulator homolog 1 (E. coli)
NCBI Gene ID		79094
neXtProt AC		NX_Q9BUX1
Human Chr (Location)		15q15.1; chr15:41245636-41248717 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	apoptotic process, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, ...
Component	cytoplasm, cytosol, ...
Function	Notch binding

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (2)    Tissues (1)   
Theiler Stages: 13

Assay Type	Results
RT-PCR	2

cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000015948 (Evidence)
Ensembl Gene Model	ENSMUSG00000027313 (Evidence)
Entrez Gene	69065 (Evidence)
UniGene	35083
DFCI	TC1582917
DoTS	DT.482128, DT.97397873
NIA Mouse Gene Index	U002311
Consensus CDS Project	CCDS16601.1
International Mouse Knockout Project Status	Chac1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000015948	VEGA Gene Model | MGI Sequence Detail	3153	C57BL/6J
transcript	OTTMUST00000037907	VEGA | MGI Sequence Detail	1637	Not Applicable
polypeptide	OTTMUSP00000017015	VEGA | MGI Sequence Detail	223	Not Applicable

All sequences(21) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(37 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013024	Butirosin biosynthesis, BtrG-like
InterPro	IPR006840	ChaC-like protein
Protein Ontology	PR:000005398	cation transport regulator-like protein 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:184017 Chi Z, et al., Botch promotes neurogenesis by antagonizing Notch. Dev Cell. 2012 Apr 17;22(4):707-20
All references(33)