About   Help   FAQ
Slc30a5
Gene Detail
 Symbol
Name
ID
Slc30a5
solute carrier family 30 (zinc transporter), member 5
MGI:1916298
Synonyms 1810010K08Rik, Znt5, ZnT-5, Zntl1, ZTL1
Feature Type protein coding gene
Genetic Map
Chromosome 13
53.23 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:100802649-100833427 bp, - strand
From Ensembl annotation of GRCm38

  30779 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41503  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc30a5

Human
homologs
Human Homolog SLC30A5, solute carrier family 30 (zinc transporter), member 5
NCBI Gene ID 64924
neXtProt AC  NX_Q8TAD4
Human Synonyms  ZnT-5, ZNT5, ZNTL1, ZTL1
Human Chr (Location)  5q12.1; chr5:69093949-69131072 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(16) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are growth retarded and exhibit skeletal defects including reduced bone density. The majority of mutant male mice die suddenly when they reach reproductive age due to bradyarrhythmia, whereas female mice live a normal term.
 
Interactions
Slc30a5 interacts with 180 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cation transport, cellular zinc ion homeostasis, ...
Component apical plasma membrane, Golgi apparatus, ...
Function cation transmembrane transporter activity, zinc ion transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (72)    Tissues (7)    Images (18)
Theiler Stages: 23
Assay TypeResults
RNA in situ 72
cDNA source data(104)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(107) cDNA(106) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000021629 (Evidence)
Entrez Gene69048 (Evidence)
UniGene402215
DFCITC1574658, TC1615494, TC1625027, TC1641936
DoTSDT.101703466, DT.40152758, DT.533875, DT.94177735, DT.94197363, DT.99851027
NIA Mouse Gene IndexU035119
Consensus CDS ProjectCCDS26739.1
International Mouse Knockout Project StatusSlc30a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021629 Ensembl Gene Model | MGI Sequence Detail 30779 C57BL/6J ±  kb
transcript ENSMUST00000067246 Ensembl | MGI Sequence Detail 3178 Not Applicable 
polypeptide ENSMUSP00000065764 Ensembl | MGI Sequence Detail 761 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(5) UniProt(4)
Polymorphisms SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002524 Cation efflux protein
InterPro IPR027469 Cation efflux protein transmembrane domain
Protein Ontology PR:000015078 zinc transporter 5
References (Earliest) J:76894 Lacourse KA, et al., Pancreatic function in CCK-deficient mice: adaptation to dietary protein does not require CCK. Am J Physiol. 1999 May;276(5 Pt 1):G1302-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)
Other
accession IDs
MGI:2159353

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory