Atp2c2
Gene Detail

Symbol Name ID

Atp2c2 ATPase, Ca++ transporting, type 2C, member 2 MGI:1916297

Synonyms

1810010G06Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 8

68.21 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:119700009-119757718 bp, + strand From NCBI annotation of GRCm38   57710 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:73463  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: Na(+)/K(+)-transporting ATPase alpha chain
Gene Tree: Atp2c2

Human homologs

Human Homolog		ATP2C2, ATPase, Ca++ transporting, type 2C, member 2
NCBI Gene ID		9914
neXtProt AC		NX_O75185
Human Synonyms		SPCA2
Human Chr (Location)		16q24.1; chr16:84402133-84497793 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	calcium ion transport, cation transport, ...
Component	integral to membrane, membrane
Function	ATP binding, calcium-transporting ATPase activity, ...

External Resources: FuncBase

Expression

cDNA source data(32)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(32) cDNA(32)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000034112 (Evidence)
Entrez Gene	69047 (Evidence)
UniGene	46251
DFCI	TC1755815
DoTS	DT.482412
NIA Mouse Gene Index	U009879
EC	3.6.3.8
Consensus CDS Project	CCDS52684.1
International Mouse Knockout Project Status	Atp2c2

Sequences

Length	Strain/Species
genomic	69047	NCBI Gene Model | MGI Sequence Detail	57710	C57BL/6J
transcript	NM_026922	RefSeq | MGI Sequence Detail	3223	Not Specified
polypeptide	A7L9Z8	UniProt | EBI | MGI Sequence Detail	944	Not Applicable

All sequences(21) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(315 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023306	ATPase, cation-transporting, domain N
InterPro	IPR008250	ATPase, P-type, ATPase-associated domain
InterPro	IPR006413	ATPase, P-type, calcium-transporting, PMR1-type
InterPro	IPR006068	ATPase, P-type cation-transporter, C-terminal
InterPro	IPR004014	ATPase, P-type cation-transporter, N-terminal
InterPro	IPR023299	ATPase, P-type, cytoplasmic domain N
InterPro	IPR023300	ATPase, P-type, cytoplasmic transduction domain A
InterPro	IPR000695	ATPase, P-type, H+ transporting proton pump
InterPro	IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter
InterPro	IPR018303	ATPase, P-type phosphorylation site
InterPro	IPR023298	ATPase, P-type, transmembrane domain
InterPro	IPR023214	HAD-like domain
InterPro	IPR005834	Haloacid dehalogenase-like hydrolase
Protein Ontology	PR:000004450	calcium-transporting ATPase type 2C member 2

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:167918 Feng M, et al., Store-independent activation of Orai1 by SPCA2 in mammary tumors. Cell. 2010 Oct 1;143(1):84-98
All references(26)