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Zg16 Gene Detail
Summary
  • Symbol
    Zg16
  • Name
    zymogen granule protein 16
  • Synonyms
    1810010M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916286
    NCBI Gene: 69036
  • Gene Overview
    MyGene.info: ZG16
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:127050156-127052705 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.30 cM, cytoband F4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916286
protein coding gene Chr7:127050156-127087328 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033019
protein coding gene Chr7:131365139-131367658 (-)
A/J MGP_AJ_G0033002
protein coding gene Chr7:127879604-127916954 (-)
AKR/J MGP_AKRJ_G0032934
protein coding gene Chr7:131114850-131160391 (-)
BALB/cJ MGP_BALBcJ_G0033007
protein coding gene Chr7:127541583-127579575 (-)
C3H/HeJ MGP_C3HHeJ_G0032717
protein coding gene Chr7:131055755-131093221 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033513
protein coding gene Chr7:136469551-136508728 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030485
protein coding gene Chr7:129091370-129093879 (-)
CAST/EiJ MGP_CASTEiJ_G0032046
protein coding gene Chr7:122846829-122849348 (-)
CBA/J MGP_CBAJ_G0032690
protein coding gene Chr7:141058715-141108905 (-)
DBA/2J MGP_DBA2J_G0032842
protein coding gene Chr7:125852237-125890140 (-)
FVB/NJ MGP_FVBNJ_G0032795
protein coding gene Chr7:125702530-125740681 (-)
LP/J MGP_LPJ_G0032936
protein coding gene Chr7:132834314-132836833 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032827
protein coding gene Chr7:142223600-142263674 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033532
protein coding gene Chr7:130130226-130167167 (-)
PWK/PhJ MGP_PWKPhJ_G0031753
protein coding gene Chr7:118848975-118851494 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031599
protein coding gene Chr7:116970660-116973176 (-)
WSB/EiJ MGP_WSBEiJ_G0032158
protein coding gene Chr7:131105880-131108399 (-)



Homology
more
  • Human Ortholog
    ZG16, zymogen granule protein 16
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZG16, zymogen granule protein 16
    Orthology source: HomoloGene, HGNC
  • Synonyms
    JCLN, JCLN1, ZG16A
  • Links
    NCBI Gene ID: 653808
    neXtProt AC: NX_O60844
    UniProt: O60844

  • Chr Location
    16p11.2; chr16:29760804-29781648 (+)  GRCh38.p7

Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased bacterial penetrance into the inner mucus layer of the colon, increased bacterial loads in draining lymph nodes and the spleen and increased abdominal fat mass.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69036 NCBI Gene Model | MGI Sequence Detail 2550 C57BL/6J ±  kb
transcript NM_026918 RefSeq | MGI Sequence Detail 682 C57BL/6  
polypeptide Q8K0C5 UniProt | EBI | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 255
    cDNA 255

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142007
References
more
  • Summaries
    All 40
    Diseases 3
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:263550 Wang W, et al., Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. J Neurosci. 2018 Jun 27;38(26):5939-5948

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory