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Zg16 Gene Detail
Summary
  • Symbol
    Zg16
  • Name
    zymogen granule protein 16
  • Synonyms
    1810010M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916286
    NCBI Gene: 69036
  • Gene Overview
    MyGene.info: ZG16
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr7:127050156-127087328 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      37173 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.30 cM, cytoband F4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ZG16, zymogen granule protein 16
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZG16, zymogen granule protein 16
    Orthology source: HomoloGene, HGNC
  • Synonyms
    JCLN, JCLN1, ZG16A
  • Links
    NCBI Gene ID: 653808
    neXtProt AC: NX_O60844
    UniProt: O60844

  • Chr Location
    16p11.2; chr16:29760804-29781648 (+)  GRCh38.p7

Human Diseases
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  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased bacterial penetrance into the inner mucus layer of the colon, increased bacterial loads in draining lymph nodes and the spleen and increased abdominal fat mass.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058493 VEGA Gene Model | MGI Sequence Detail 37173 C57BL/6J ±  kb
transcript OTTMUST00000143635 VEGA | MGI Sequence Detail 682 Not Applicable  
polypeptide OTTMUSP00000074878 VEGA | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    329 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
less
  • All nucleic 254
    cDNA 254

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142007
References
more
  • Summaries
    All 38
    Diseases 3
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239106 Mufazalov IA, et al., IL-1 signaling is critical for expansion but not generation of autoreactive GM-CSF+ Th17 cells. EMBO J. 2017 Jan 04;36(1):102-115

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory