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Anapc10 Gene Detail
Summary
  • Symbol
    Anapc10
  • Name
    anaphase promoting complex subunit 10
  • Synonyms
    1500026N15Rik, A830003M23Rik, Apc10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916249
    NCBI Gene: 68999
  • Gene Overview
    MyGene.info: ANAPC10
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:80438366-80503950 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 37.79 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916249
protein coding gene Chr8:80438366-80505688 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033815
protein coding gene Chr8:80401192-80472681 (+)
A/J MGP_AJ_G0033797
protein coding gene Chr8:77205276-77261139 (+)
AKR/J MGP_AKRJ_G0033724
protein coding gene Chr8:79511722-79568995 (+)
BALB/cJ MGP_BALBcJ_G0033791
protein coding gene Chr8:77319422-77379143 (+)
C3H/HeJ MGP_C3HHeJ_G0033500
protein coding gene Chr8:80145427-80210754 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034311
protein coding gene Chr8:83483281-83553187 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031252
protein coding gene Chr8:71266659-71320944 (+)
CAST/EiJ MGP_CASTEiJ_G0032831
protein coding gene Chr8:79480277-79546311 (+)
CBA/J MGP_CBAJ_G0033479
protein coding gene Chr8:86418731-86486153 (+)
DBA/2J MGP_DBA2J_G0033632
protein coding gene Chr8:76900830-76961981 (+)
FVB/NJ MGP_FVBNJ_G0033577
protein coding gene Chr8:75869155-75926488 (+)
LP/J MGP_LPJ_G0033722
protein coding gene Chr8:80480027-80548600 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033620
protein coding gene Chr8:88980738-89047502 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034328
protein coding gene Chr8:79533850-79594553 (+)
PWK/PhJ MGP_PWKPhJ_G0032534
protein coding gene Chr8:76173251-76237229 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032372
protein coding gene Chr8:78343805-78400544 (+)
WSB/EiJ MGP_WSBEiJ_G0032944
protein coding gene Chr8:79865153-79927801 (+)



Homology
more
  • Human Ortholog
    ANAPC10, anaphase promoting complex subunit 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANAPC10, anaphase promoting complex subunit 10
  • Synonyms
    APC10, DOC1
  • Links
    NCBI Gene ID: 10393
    neXtProt AC: NX_Q9UM13
    UniProt: Q9UM13

  • Chr Location
    4q31.21; chr4:144967117-145098541 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    37 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68999 NCBI Gene Model | MGI Sequence Detail 65585 C57BL/6J ±  kb
transcript NM_001357236 RefSeq | MGI Sequence Detail 2903 C57BL/6  
polypeptide Q8K2H6 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGI:2441829
References
more
  • Summaries
    All 61
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 37
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:306807 Saito K, et al., Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. iScience. 2020 Jul 24;23(7):101329

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory