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Mcts1 Gene Detail
Summary
  • Symbol
    Mcts1
  • Name
    malignant T cell amplified sequence 1
  • Synonyms
    1500019M23Rik, MCT-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916245
    NCBI Gene: 68995
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:38600578-38613426 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 22.88 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916245
 protein coding gene ChrX:38600444-38613524 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035667
 protein coding gene ChrX:33572409-33588448 (+)
A/J MGP_AJ_G0035652
 protein coding gene ChrX:33622523-33640840 (+)
AKR/J MGP_AKRJ_G0035569
 protein coding gene ChrX:34418101-34433010 (+)
BALB/cJ MGP_BALBcJ_G0035636
 protein coding gene ChrX:33328427-33341867 (+)
C3H/HeJ MGP_C3HHeJ_G0035340
 protein coding gene ChrX:33935747-33951674 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036167
 protein coding gene ChrX:34341767-34360493 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033019
 protein coding gene ChrX:32034495-32045225 (+)
CAST/EiJ MGP_CASTEiJ_G0034631
 protein coding gene ChrX:21932185-21950396 (+)
CBA/J MGP_CBAJ_G0035314
 protein coding gene ChrX:35209292-35225286 (+)
DBA/2J MGP_DBA2J_G0035468
 protein coding gene ChrX:33462112-33474336 (+)
FVB/NJ MGP_FVBNJ_G0035417
 protein coding gene ChrX:33211205-33224047 (+)
LP/J MGP_LPJ_G0035556
 protein coding gene ChrX:33972175-33984791 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035455
 protein coding gene ChrX:35542508-35558965 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036183
 protein coding gene ChrX:33617077-33633547 (+)
PWK/PhJ MGP_PWKPhJ_G0034332
 protein coding gene ChrX:21514631-21527622 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034177
 protein coding gene ChrX:22477792-22492406 (+)
WSB/EiJ MGP_WSBEiJ_G0034777
 protein coding gene ChrX:33297936-33313837 (+)



Homology
more
  • Human Ortholog
    MCTS1, MCTS1 re-initiation and release factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MCTS1, MCTS1 re-initiation and release factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MCT1, MCT-1
  • Links
    NCBI Gene ID: 28985
    neXtProt AC: NX_Q9ULC4
    UniProt: Q9ULC4

  • Chr Location
    Xq24; chrX:120603889-120621159 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    63
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000355 Ensembl Gene Model | MGI Sequence Detail 12849 C57BL/6J ±  kb
transcript ENSMUST00000000365 Ensembl | MGI Sequence Detail 783 Not Applicable  
polypeptide ENSMUSP00000000365 Ensembl | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 63

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:237626 Kwon SH, et al., Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex. J Biol Chem. 2016 Dec 02;291(49):25462-25475
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory