Tamm41 MGI Mouse Gene Detail - MGI:1916221 - TAM41 mitochondrial translocator assembly and maintenance homolog

Symbol

Tamm41
Name

TAM41 mitochondrial translocator assembly and maintenance homolog
Synonyms

1500001M20Rik

Feature Type

protein coding gene
IDs

MGI:1916221
NCBI Gene: 68971
Alliance

genome feature page
Transcription Start Sites

1 TSS

Sequence Map

Chr6:114981342-115014837 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 53.14 cM, cytoband E3
Mapping Data

2 experiments

SNPs within 2kb

1010 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916221	protein coding gene	Chr6:114981342-115014890 (-)
129S1/SvImJ	ENSMUSG00200024164	protein coding gene	Chr6:112196666-112230157 (-)
A/J	ENSMUSG00195016147	protein coding gene	Chr6:111587199-111620695 (-)
AKR/J	ENSMUSG00220031870	protein coding gene	Chr6:110499500-110533322 (-)
BALB/cJ	ENSMUSG00180002242	protein coding gene	Chr6:111952902-111986397 (-)
C3H/HeJ	ENSMUSG00175031668	protein coding gene	Chr6:65447554-65481378 (+)
C57BL/6NJ	ENSMUSG00215018963	protein coding gene	Chr6:111940008-111973503 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028747	protein coding gene	Chr6:110108435-110142496 (-)
CAST/EiJ	ENSTCUG00005028798	protein coding gene	Chr6:111802247-111836063 (-)
CBA/J	ENSMUSG00210020315	protein coding gene	Chr6:111756529-111790350 (-)
DBA/2J	ENSMUSG00185046301	protein coding gene	Chr6:112395184-112428675 (-)
FVB/NJ	ENSMUSG00205014855	protein coding gene	Chr6:110823226-110856920 (-)
JF1/MsJ	ENSUMUG00000016822	protein coding gene	Chr6:111049182-111082999 (-)
LP/J	ENSMUSG00230042278	protein coding gene	Chr6:113599545-113633036 (-)
NOD/ShiLtJ	ENSMUSG00190016596	protein coding gene	Chr6:111349392-111382883 (-)
NZO/HlLtJ	ENSMUSG00225047026	protein coding gene	Chr6:115455268-115488759 (-)
PWK/PhJ	ENSLUMG00010024944	protein coding gene	Chr6:110351583-110385414 (-)
SPRET/EiJ	ENSMSPG00010036206	protein coding gene	Chr6:113145959-113179814 (-)
WSB/EiJ	ENSIUOG00005023082	protein coding gene	Chr6:112085494-112118955 (-)

Human Ortholog

TAMM41, TAM41 mitochondrial translocator assembly and maintenance homolog

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TAMM41, TAM41 mitochondrial translocator assembly and maintenance homolog
Synonyms

C3orf31, COXPD56, RAM41, TAM41
Links

HGNC:25187

NCBI Gene ID: 132001

UniProt: Q96BW9
Chr Location

3p25.2; chr3:11721896-11846919 (-) GRCh38

MGI Vertebrate Homology

Tamm41 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TAMM41
Protein SuperFamily

Mmp37
Gene Tree

Tamm41

Diseases

1 with human TAMM41 associations

				Human Disease	Mouse Models
				combined oxidative phosphorylation deficiency 56 IDs combined oxidative phosphorylation deficiency 56 DOID:0070429 OMIM:620139

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

2 phenotypes from 2 alleles in 2 genetic backgrounds
17 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

12
Endonuclease-mediated

2
Gene trapped

4
Spontaneous

1
Targeted

5
Genomic Mutations

1 involving Tamm41
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

18 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a knock-out allele exhibit embryonic lethality.

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All GO Annotations

18
GO References

11

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

23

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN tamm41

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All Sequences

55
RefSeq

7
UniProt

5
CCDS

CCDS20437.1

Ensembl

ENSMUSG00000030316 (Evidence)
NCBI Gene

68971

			Length	Strain/Species	Flank
genomic	ENSMUSG00000030316	Ensembl Gene Model \| MGI Sequence Detail	33496	C57BL/6J	± kb
transcript	ENSMUST00000032461	Ensembl \| MGI Sequence Detail	1168	Not Applicable
polypeptide	ENSMUSP00000032461	Ensembl \| MGI Sequence Detail	337	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000031492 phosphatidate cytidylyltransferase, mitochondrial

(term hierarchy)
EC

2.7.7.41
InterPro Domains

IPR015222 Phosphatidate cytidylyltransferase, mitochondrial

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All nucleic 23

cDNA 23

Microarray probesets 3

Summaries

All 49

Gene Ontology 11

Phenotypes 17
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376

TSS for Tamm41:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr62499	Chr6:115014785-115014842 (-)	23 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/15/2026 MGI 6.29