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Cdan1 Gene Detail
Summary
  • Symbol
    Cdan1
  • Name
    codanin 1
  • Synonyms
    1500015A01Rik, CDA1, CDA-I, codanin-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916218
    NCBI Gene: 68968
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120546635-120561998 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    62 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916218
 protein coding gene Chr2:120546635-120680609 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026373
 protein coding gene Chr2:123590214-123716784 (-)
A/J MGP_AJ_G0026334
 protein coding gene Chr2:118534580-118655385 (-)
AKR/J MGP_AKRJ_G0026313
 protein coding gene Chr2:121842480-121978633 (-)
BALB/cJ MGP_BALBcJ_G0026347
 protein coding gene Chr2:118773512-118893480 (-)
C3H/HeJ MGP_C3HHeJ_G0026093
 protein coding gene Chr2:122344010-122468343 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026794
 protein coding gene Chr2:127630781-127770637 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024174
 protein coding gene Chr2:113547160-113688841 (-)
CAST/EiJ MGP_CASTEiJ_G0025555
 protein coding gene Chr2:122644960-122769660 (-)
CBA/J MGP_CBAJ_G0026069
 protein coding gene Chr2:132092788-132223379 (-)
DBA/2J MGP_DBA2J_G0026208
 protein coding gene Chr2:117926609-118044279 (-)
FVB/NJ MGP_FVBNJ_G0026170
 protein coding gene Chr2:116758330-116878808 (-)
LP/J MGP_LPJ_G0026309
 protein coding gene Chr2:123854360-123978433 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026189
 protein coding gene Chr2:136393552-136523343 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026849
 protein coding gene Chr2:121974402-122102806 (-)
PWK/PhJ MGP_PWKPhJ_G0025291
 protein coding gene Chr2:117528281-117658053 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025090
 protein coding gene Chr2:121177590-121318620 (-)
WSB/EiJ MGP_WSBEiJ_G0025624
 protein coding gene Chr2:122805127-122932758 (-)



Homology
more
  • Human Ortholog
    CDAN1, codanin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDAN1, codanin 1
  • Synonyms
    CDA1, CDAI, CDAN1A, DLT, PRO1295
  • Links
    NCBI Gene ID: 146059
    neXtProt AC: NX_Q8IWY9
    UniProt: Q8IWY9

  • Chr Location
    15q15.2; chr15:42723544-42737128 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CDAN1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 3 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit complete embryonic lethality between implantation and somite formation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    812
  • Tissues
    37
  • cDNA Data
    9
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68968 NCBI Gene Model | MGI Sequence Detail 15364 C57BL/6J ±  kb
    transcript NM_026891 RefSeq | MGI Sequence Detail 6384 C57BL/6  
    polypeptide Q8CC12 UniProt | EBI | MGI Sequence Detail 1239 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138950, MGI:2139352
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:307952 Noy-Lotan S, et al., Cdan1 Is Essential for Primitive Erythropoiesis. Front Physiol. 2021;12:685242
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory