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Chmp2b
Gene Detail
 Symbol
Name
ID
Chmp2b
charged multivesicular body protein 2B
MGI:1916192
Synonyms 1190006E07Rik, chromatin modifying protein 2B
Feature Type protein coding gene
Genetic Map
Chromosome 16
37.26 cM, cytoband C1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:65539133-65562697 bp, - strand
From NCBI annotation of GRCm38

  23565 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8534  Vertebrate Homology Class
1 human; 1 mouse; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ESCRT-3 complex, Chmp1/Chmp2/Chmp3 subunits
Gene Tree: Chmp2b

Human
homologs
Human Homolog CHMP2B, charged multivesicular body protein 2B
NCBI Gene ID 25978
neXtProt AC  NX_Q9UQN3
Human Synonyms  ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B
Human Chr (Location)  3p11.2; chr3:87227263-87255548 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human CHMP2B
Alleles
and
phenotypes
All alleles(5) : Targeted(2) Gene trapped(3)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process protein transport, transport
Component cytoplasm, endosome, ...
Function protein domain specific binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (58)    Tissues (8)    Images (29)
Theiler Stages: 23
Assay TypeResults
RNA in situ 58
cDNA source data(66)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(66) cDNA(66)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000004843 (Evidence)
Entrez Gene68942 (Evidence)
UniGene432944
DFCITC1575081
DoTSDT.101405429
NIA Mouse Gene IndexU037179
Consensus CDS ProjectCCDS28269.1
International Mouse Knockout Project StatusChmp2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68942 NCBI Gene Model | MGI Sequence Detail 23565 C57BL/6J ±  kb
transcript NM_026879 RefSeq | MGI Sequence Detail 1838 C57BL/6 
polypeptide Q8BJF9 UniProt | EBI | MGI Sequence Detail 213 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005024 Snf7
Protein Ontology PR:000005435 charged multivesicular body protein 2b
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:195640 Xu J, et al., Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS One. 2012;7(12):e48573
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory