Chmp2b
Gene Detail

Symbol Name ID

Chmp2b charged multivesicular body protein 2B MGI:1916192

Synonyms

1190006E07Rik, chromatin modifying protein 2B

Feature Type

protein coding gene

Genetic Map

Chromosome 16

37.26 cM, cytoband C1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr16:65539133-65562697 bp, - strand From NCBI annotation of GRCm38   23565 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; cattle; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Chmp2b ± 2 cM)

Protein SuperFamily: ESCRT-3 complex, Chmp1/Chmp2/Chmp3 subunits
Gene Tree: Chmp2b

Human ortholog

CHMP2B charged multivesicular body protein 2B NCBI Gene ID 25978
Human Synonyms: ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B
Human Chr3:87276413-87304698 bp, + strand Reference GRCh37.p2 Primary Assembly
Human Diseases Associated with Human CHMP2B (2)

Alleles and phenotypes

All alleles(5) : Targeted(2) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	protein transport, transport
Component	cytoplasm, endosome, ...
Function	protein domain specific binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (58)    Tissues (8)    Images (29)
Theiler Stages: 23

Assay Type	Results
RNA in situ	58

cDNA source data(68)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(68) cDNA(68)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000004843 (Evidence)
Entrez Gene	68942 (Evidence)
UniGene	432944
DFCI	TC1575081
DoTS	DT.101405429
NIA Mouse Gene Index	U037179
Consensus CDS Project	CCDS28269.1
International Mouse Knockout Project Status	Chmp2b

Sequences

Length	Strain/Species
genomic	68942	NCBI Gene Model | MGI Sequence Detail	23565	C57BL/6J
transcript	NM_026879	RefSeq | MGI Sequence Detail	1838	C57BL/6
polypeptide	Q8BJF9	UniProt | EBI | MGI Sequence Detail	213	Not Applicable

All sequences(34) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(121 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005024	Snf7
Protein Ontology	PR:000005435	charged multivesicular body protein 2b

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)