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Rpap1 Gene Detail
Summary
  • Symbol
    Rpap1
  • Name
    RNA polymerase II associated protein 1
  • Synonyms
    1190005L06Rik, A730023M06Rik, mKIAA1403
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916175
    NCBI Gene: 68925
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:119763959-119787537 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    232 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916175
protein coding gene Chr2:119763304-119787537 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026352
protein coding gene Chr2:122593647-122620254 (-)
A/J MGP_AJ_G0026313
protein coding gene Chr2:117572795-117597231 (-)
AKR/J MGP_AKRJ_G0026292
protein coding gene Chr2:120854508-120879053 (-)
BALB/cJ MGP_BALBcJ_G0026326
protein coding gene Chr2:117814207-117838188 (-)
C3H/HeJ MGP_C3HHeJ_G0026072
protein coding gene Chr2:121316154-121343237 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026773
protein coding gene Chr2:126582295-126609270 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024153
protein coding gene Chr2:112600813-112624868 (-)
CAST/EiJ MGP_CASTEiJ_G0025534
protein coding gene Chr2:121636701-121662421 (-)
CBA/J MGP_CBAJ_G0026048
protein coding gene Chr2:131025389-131050559 (-)
DBA/2J MGP_DBA2J_G0026187
protein coding gene Chr2:116968968-116992840 (-)
FVB/NJ MGP_FVBNJ_G0026149
protein coding gene Chr2:115800067-115824094 (-)
LP/J MGP_LPJ_G0026288
protein coding gene Chr2:122858626-122882070 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026168
protein coding gene Chr2:135346927-135371375 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026828
protein coding gene Chr2:120974519-121000214 (-)
PWK/PhJ MGP_PWKPhJ_G0025270
protein coding gene Chr2:116553666-116578339 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025069
protein coding gene Chr2:120161277-120187195 (-)
WSB/EiJ MGP_WSBEiJ_G0025603
protein coding gene Chr2:121807783-121833539 (-)



Homology
more
  • Human Ortholog
    RPAP1, RNA polymerase II associated protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RPAP1, RNA polymerase II associated protein 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 26015
    neXtProt AC: NX_Q9BWH6
    UniProt: Q9BWH6

  • Chr Location
    15q15.1; chr15:41517176-41544277 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32269
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RPAP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68925 NCBI Gene Model | MGI Sequence Detail 23579 C57BL/6J ±  kb
transcript NM_177294 RefSeq | MGI Sequence Detail 4822 C57BL/6  
polypeptide Q80TE0 UniProt | EBI | MGI Sequence Detail 1409 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000014175 RNA polymerase II-associated protein 1
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR013929 RNA polymerase II-associated protein 1, C-terminal
    IPR013930 RNA polymerase II-associated protein 1, N-terminal
    IPR039913 RNA polymerase II-associated protein RPAP1/Rba50
Molecular
Reagents
less
  • All nucleic 100
    cDNA 100

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139213, MGI:2139298, MGI:2445058
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory