About   Help   FAQ
Disp1
Gene Detail
 Symbol
Name
ID
Disp1
dispatched homolog 1 (Drosophila)
MGI:1916147
Synonyms 1190008H24Rik, DispA
Feature Type protein coding gene
Genetic Map
Chromosome 1
Syntenic

Mapping data(2)
Sequence Map
Chr1:183086264-183221529 bp, - strand
From NCBI annotation of GRCm38

  135266 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14133  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Disp1

Human
homologs
Human Homolog DISP1, dispatched homolog 1 (Drosophila)
NCBI Gene ID 84976
neXtProt AC  NX_Q96F81
Human Synonyms  DISPA
Human Chr (Location)  1q41; chr1:222815089-223005995 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Chemically induced (ENU)(1) Gene trapped(6) Targeted(5)
Incidental mutations (data from Mutagenetix )
 
Mice homozygous for targeted and chemically induced mutations exhibit a dorsalized neural tube, impaired heart looping, pericardial edema, large forelimbs, and abnormal head shape.
 
Alleles Annotated to Human Diseases(2)   
Interactions
Disp1 interacts with 31 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process determination of left/right symmetry, diaphragm development, ...
Component integral component of membrane, membrane
Function hedgehog receptor activity, peptide transporter activity
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (62)    Tissues (36)    Images (27)
Theiler Stages: 12, 14, 15, 17, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 61
Northern blot 1
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000030768 (Evidence)
Entrez Gene68897 (Evidence)
DFCITC1578610, TC1652175, TC1660213
DoTSDT.101387519, DT.40135624, DT.40144994
NIA Mouse Gene IndexU040488, U053586
Consensus CDS ProjectCCDS56661.1
International Mouse Knockout Project StatusDisp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68897 NCBI Gene Model | MGI Sequence Detail 135266 C57BL/6J ±  kb
transcript NM_026866 RefSeq | MGI Sequence Detail 5030 C57BL/6 
polypeptide Q3TDN0 UniProt | EBI | MGI Sequence Detail 1521 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(823 from dbSNP Build 137)    SNPs within 2kb including multiple locations(825)
Protein-related
information
ResourceIDDescription
InterPro IPR003392 Patched
InterPro IPR000731 Sterol-sensing domain
Protein Ontology PR:000006495 protein dispatched homolog 1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:171050 Thiagarajan RD, et al., Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/16/2014
MGI 5.19
The Jackson Laboratory