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Disp1 Gene Detail
Summary
  • Symbol
    Disp1
  • Name
    dispatched RND transporter family member 1
  • Synonyms
    1190008H24Rik, DispA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916147
    NCBI Gene: 68897
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:182867830-183003086 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    800 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916147
 protein coding gene Chr1:182867828-183010257 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016900
 protein coding gene Chr1:189723406-189861801 (-)
A/J MGP_AJ_G0016879
 protein coding gene Chr1:181971646-182108182 (-)
AKR/J MGP_AKRJ_G0016844
 protein coding gene Chr1:187377322-187520677 (-)
BALB/cJ MGP_BALBcJ_G0016837
 protein coding gene Chr1:182609997-182751231 (-)
C3H/HeJ MGP_C3HHeJ_G0016661
 protein coding gene Chr1:188185626-188324703 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017300
 protein coding gene Chr1:195807003-195956018 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015007
 protein coding gene Chr1:173034917-173165034 (-)
CAST/EiJ MGP_CASTEiJ_G0016243
 protein coding gene Chr1:187559059-187713237 (-)
CBA/J MGP_CBAJ_G0016635
 protein coding gene Chr1:203094909-203253413 (-)
DBA/2J MGP_DBA2J_G0016741
 protein coding gene Chr1:180749234-180890044 (-)
FVB/NJ MGP_FVBNJ_G0016737
 protein coding gene Chr1:178885286-179022816 (-)
LP/J MGP_LPJ_G0016816
 protein coding gene Chr1:190902699-191050868 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016769
 protein coding gene Chr1:210062530-210218158 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017337
 protein coding gene Chr1:187208959-187348059 (-)
PWK/PhJ MGP_PWKPhJ_G0016031
 protein coding gene Chr1:179941680-180074257 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015807
 protein coding gene Chr1:186161208-186308562 (-)
WSB/EiJ MGP_WSBEiJ_G0016306
 protein coding gene Chr1:187387789-187529284 (-)



Homology
more
  • Human Ortholog
    DISP1, dispatched RND transporter family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DISP1, dispatched RND transporter family member 1
  • Synonyms
    DISPA
  • Links
    NCBI Gene ID: 84976
    neXtProt AC: NX_Q96F81
    UniProt: Q96F81

  • Chr Location
    1q41; chr1:222814514-223005995 (+)  GRCh38.p7
Human Diseases
less
  • Mutations/Alleles
    2 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    64 phenotypes from 6 alleles in 6 genetic backgrounds
    16 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for targeted and chemically induced mutations exhibit a dorsalized neural tube, impaired heart looping, pericardial edema, large forelimbs, and abnormal head shape.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    744
  • Tissues
    46
  • cDNA Data
    13
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030768 Ensembl Gene Model | MGI Sequence Detail 135257 C57BL/6J ±  kb
    transcript ENSMUST00000195372 Ensembl | MGI Sequence Detail 4901 Not Applicable  
    polypeptide ENSMUSP00000141747 Ensembl | MGI Sequence Detail 1521 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 13
      Other 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 10
      Diseases 1
      Gene Ontology 8
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:302594 Hall ET, et al., Cytoneme delivery of sonic hedgehog from ligand-producing cells requires Myosin 10 and a dispatched-BOC/CDON co-receptor complex. Elife. 2021 Feb 11;10:e61432
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/23/2022
    MGI 6.20     		The Jackson Laboratory