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Urah
Gene Detail
 Symbol
Name
ID
Urah
urate (5-hydroxyiso-) hydrolase
MGI:1916142
Synonyms 1190003J15Rik, 2810420C16Rik, HIU hydrolase
Feature Type protein coding gene
Genetic Map
Chromosome 7
86.03 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:140835018-140837966 bp, + strand
From VEGA annotation of GRCm38

  2949 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45975  Vertebrate Homology Class
1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 2 zebrafish

Protein SuperFamily: transthyretin/transthyretin-related protein
Gene Tree: Urah

Alleles
and
phenotypes
All alleles(9) : Chemically induced (ENU)(1) Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU mutation have an elevated platelet cell number, display hepatomegaly and hepatocellular carcinoma.
 
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process purine nucleobase metabolic process, transport
Component mitochondrion, peroxisome
Function hydrolase activity, hydroxyisourate hydrolase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024526 (Evidence)
Ensembl Gene ModelENSMUSG00000025481 (Evidence)
Entrez Gene76974 (Evidence)
DFCITC1582402
DoTSDT.532352, DT.94234306
NIA Mouse Gene IndexU040692
EC3.5.2.17
Consensus CDS ProjectCCDS21986.1
International Mouse Knockout Project StatusUrah
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024526 VEGA Gene Model | MGI Sequence Detail 2949 C57BL/6J ±  kb
transcript OTTMUST00000060193 VEGA | MGI Sequence Detail 719 Not Applicable 
polypeptide OTTMUSP00000029354 VEGA | MGI Sequence Detail 118 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014306 Hydroxyisourate hydrolase
InterPro IPR023419 Transthyretin, conserved site
InterPro IPR000895 Transthyretin/hydroxyisourate hydrolase
InterPro IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily
Protein Ontology PR:000017227 5-hydroxyisourate hydrolase
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:1924224

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory