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Foxk2
Gene Detail
Symbol

Name
ID
Foxk2
forkhead box K2
MGI:1916087
Synonyms
1110054H05Rik, 5730434B08Rik, Ilf1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
85.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:121259990-121309896 bp, + strand
From VEGA annotation of GRCm38

  49907 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18748  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FOXK2
Gene Tree: Foxk2

Human
homologs
FOXK2, forkhead box K2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 3607
neXtProt AC: NX_Q01167

Human Synonyms: ILF, ILF1, ILF-1

Human Chr (Location): 17q25; chr17:82519718-82604607 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(7)
Incidental mutations (data from APF )
Interactions
Foxk2 interacts with 335 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process anatomical structure morphogenesis, cell differentiation, ...
Component intracellular membrane-bounded organelle, nucleoplasm, ...
Function DNA binding, magnesium ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (230)    Tissues (162)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 228
RT-PCR 2
cDNA source data(145)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA FOXK2 ; Xenbase foxk2    NEW 
Molecular
reagents
All nucleic(149) Genomic(1) cDNA(146) Primer pair(1) Other(1)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000004287 (Evidence)
Ensembl Gene Model ENSMUSG00000039275 (Evidence)
Entrez Gene 68837 (Evidence)
UniGene 209750
DFCI TC1600448, TC1600612, TC1602338, TC1604564
DoTS DT.101235961, DT.101388058, DT.491076, DT.87056064
NIA Mouse Gene Index U013686
Consensus CDS Project CCDS36393.2
International Mouse Phenotyping Consortium Status Foxk2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004287 VEGA Gene Model | MGI Sequence Detail 49907 C57BL/6J ±  kb
transcript OTTMUST00000009717 VEGA | MGI Sequence Detail 5029 Not Applicable 
polypeptide OTTMUSP00000004677 VEGA | MGI Sequence Detail 651 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(15) UniProt(2)
Polymorphisms
SNPs within 2kb(202 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000253 Forkhead-associated (FHA) domain
InterPro IPR008984 SMAD/FHA domain
InterPro IPR001766 Transcription factor, fork head
InterPro IPR018122 Transcription factor, fork head, conserved site
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007632 forkhead box protein K2
References
(Earliest) J:39656 Farrington SM, et al., Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev. 1997 Mar;62(2):197-211
(Latest) J:216294 Kumar A, et al., Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development. Int J Dev Neurosci. 2014 Nov;38:138-46
All references(37)
Other
accession IDs
MGI:1913885, MGI:891988

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory