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Foxk2 Gene Detail
Summary
  • Symbol
    Foxk2
  • Name
    forkhead box K2
  • Synonyms
    1110054H05Rik, 5730434B08Rik, Ilf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916087
    NCBI Gene: 68837
  • Gene Overview
    MyGene.info: FOXK2
Location & Maps
more
  • Sequence Map
    Chr11:121259990-121309896 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      49907 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 85.15 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FOXK2, forkhead box K2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FOXK2, forkhead box K2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ILF, ILF1, ILF-1
  • Links
    NCBI Gene ID: 3607
    neXtProt AC: NX_Q01167

  • Chr Location
    17q25; chr17:82519718-82604607 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18748
    1 human;1 mouse;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: FOXK2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    8
  • Endonuclease-mediated
    1
  • Gene trapped
    7
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004287 VEGA Gene Model | MGI Sequence Detail 49907 C57BL/6J ±  kb
transcript OTTMUST00000009717 VEGA | MGI Sequence Detail 5029 Not Applicable  
polypeptide OTTMUSP00000004677 VEGA | MGI Sequence Detail 651 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    202 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 149
    Genomic 1
    cDNA 146
    Primer pair 1
    Other 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1913885, MGI:891988
References
more
  • Summaries
    All 36
    Developmental Gene Expression 9
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:39656 Farrington SM, et al., Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev. 1997 Mar;62(2):197-211
  • Latest
    J:217746 Bowman CJ, et al., Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. Nat Cell Biol. 2014 Dec;16(12):1202-14

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory