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Foxk2 Gene Detail
Summary
  • Symbol
    Foxk2
  • Name
    forkhead box K2
  • Synonyms
    1110054H05Rik, 5730434B08Rik, Ilf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916087
    NCBI Gene: 68837
  • Gene Overview
    MyGene.info: FOXK2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:121259990-121309896 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 85.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    202 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916087
protein coding gene Chr11:121259987-121309896 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019545
protein coding gene Chr11:125820879-125853843 (+)
A/J MGP_AJ_G0019512
protein coding gene Chr11:120178141-120232891 (+)
AKR/J MGP_AKRJ_G0019482
protein coding gene Chr11:123820619-123872926 (+)
BALB/cJ MGP_BALBcJ_G0019487
protein coding gene Chr11:120548575-120597712 (+)
C3H/HeJ MGP_C3HHeJ_G0019293
protein coding gene Chr11:124144102-124201997 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019936
protein coding gene Chr11:129612380-129678586 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017561
protein coding gene Chr11:117162178-117212471 (+)
CAST/EiJ MGP_CASTEiJ_G0018847
protein coding gene Chr11:125649228-125701241 (+)
CBA/J MGP_CBAJ_G0019264
protein coding gene Chr11:134649284-134703236 (+)
DBA/2J MGP_DBA2J_G0019377
protein coding gene Chr11:119549058-119602308 (+)
FVB/NJ MGP_FVBNJ_G0019368
protein coding gene Chr11:119269684-119318941 (+)
LP/J MGP_LPJ_G0019448
protein coding gene Chr11:126075122-126131632 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019401
protein coding gene Chr11:133461437-133512806 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019975
protein coding gene Chr11:124508511-124559882 (+)
PWK/PhJ MGP_PWKPhJ_G0018614
protein coding gene Chr11:120993247-121043919 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018405
protein coding gene Chr11:124259435-124309383 (+)
WSB/EiJ MGP_WSBEiJ_G0018900
protein coding gene Chr11:124476154-124529855 (+)



Homology
more
  • Human Ortholog
    FOXK2, forkhead box K2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FOXK2, forkhead box K2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ILF, ILF1, ILF-1
  • Links
    NCBI Gene ID: 3607
    neXtProt AC: NX_Q01167
    UniProt: Q01167

  • Chr Location
    17q25.3; chr17:82519718-82604607 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18748
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FOXK2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039275 Ensembl Gene Model | MGI Sequence Detail 49907 C57BL/6J ±  kb
transcript ENSMUST00000106113 Ensembl | MGI Sequence Detail 5029 Not Applicable  
polypeptide ENSMUSP00000101719 Ensembl | MGI Sequence Detail 651 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 149
    Genomic 2
    cDNA 146
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1913885, MGI:891988
References
more
  • Summaries
    All 39
    Developmental Gene Expression 10
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:39656 Farrington SM, et al., Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev. 1997 Mar;62(2):197-211
  • Latest
    J:239289 Wang W, et al., FOXKs promote Wnt/beta-catenin signaling by translocating DVL into the nucleus. Dev Cell. 2015 Mar 23;32(6):707-18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory