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Ldah
Gene Detail
Symbol

Name
ID
Ldah
lipid droplet associated hydrolase
MGI:1916082
Synonyms
1110057K04Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 12
3.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:8208107-8285758 bp, + strand
From Ensembl annotation of GRCm38

  77652 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41453  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LDAH
Gene Tree: Ldah

Human
homologs
LDAH, lipid droplet associated hydrolase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 60526
neXtProt AC: NX_Q9H6V9

Human Synonyms: C2orf43, hLDAH

Human Chr (Location): 2p24.1; chr2:20684014-20823137 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(12) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ldah interacts with 217 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(83)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(83) cDNA(83)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000037669 (Evidence)
Entrez Gene 68832 (Evidence)
UniGene 25608
DFCI TC1576277, TC1580482, TC1595955, TC1603976, TC1620805, TC1637965, TC1688564
DoTS DT.101156739, DT.101723625, DT.110934701, DT.55101210, DT.55113587, DT.55190053
NIA Mouse Gene Index U013737
EC 3.1.1.-
Consensus CDS Project CCDS25798.1, CCDS49023.1
International Mouse Phenotyping Consortium Status Ldah
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037669 Ensembl Gene Model | MGI Sequence Detail 77652 C57BL/6J ±  kb
transcript ENSMUST00000037383 Ensembl | MGI Sequence Detail 2736 Not Applicable 
polypeptide ENSMUSP00000042285 Ensembl | MGI Sequence Detail 326 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(16) UniProt(3)
Polymorphisms
SNPs within 2kb(510 from dbSNP Build 137)    SNPs within 2kb including multiple locations(524)
Protein-related
information
ResourceIDDescription
InterPro IPR029058 Alpha/Beta hydrolase fold
InterPro IPR019363 Lipid droplet-associated hydrolase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:221549 Goo YH, et al., Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization. Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):386-96
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory