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Elovl5
Gene Detail
Symbol

Name
ID
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
MGI:1916051
Synonyms
1110059L23Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
43.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:77917364-77984519 bp, + strand
From VEGA annotation of GRCm38

  67156 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41449  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ELOVL5
Gene Tree: Elovl5

Human
homologs
ELOVL5, ELOVL fatty acid elongase 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 60481
neXtProt AC: NX_Q9NYP7

Human Synonyms: dJ483K16.1, HELO1, SCA38

Human Chr (Location): 6p12.1; chr6:53267398-53349179 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ELOVL5

Mutations,
alleles, and
phenotypes
All mutations/alleles(149) : Gene trapped(146) Radiation induced(1) Targeted(2)
Genomic Mutations involving Elovl5 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele have defects in fatty acid synthesis in the liver that result in hepatic steatosis. Also, majority of female mice have defects in female fertility.
 
Interactions
Elovl5 interacts with 307 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (96)    Tissues (95)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
RT-PCR 2
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase elovl5 ; ZFIN elovl5    NEW 
Molecular
reagents
All nucleic(20) cDNA(19) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000022986 (Evidence)
Ensembl Gene Model ENSMUSG00000032349 (Evidence)
Entrez Gene 68801 (Evidence)
DFCI TC1573390
DoTS DT.91360977, DT.101737958, DT.534201, DT.101381056
NIA Mouse Gene Index U010772
EC 2.3.1.199
Consensus CDS Project CCDS23355.1
International Mouse Phenotyping Consortium Status Elovl5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022986 VEGA Gene Model | MGI Sequence Detail 67156 C57BL/6J ±  kb
transcript OTTMUST00000055326 VEGA | MGI Sequence Detail 2782 Not Applicable 
polypeptide OTTMUSP00000026486 VEGA | MGI Sequence Detail 299 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(476 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002076 GNS1/SUR4 membrane protein
Protein Ontology PR:000007040 elongation of very long chain fatty acids protein 5
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:216600 Lau CG, et al., Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil. Mol Reprod Dev. 2014 Nov;81(11):994-1008
All references(43)
Other
accession IDs
MGI:2143114, MGI:2143235

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory