About   Help   FAQ
Elovl5 Gene Detail
Summary
  • Symbol
    Elovl5
  • Name
    ELOVL family member 5, elongation of long chain fatty acids (yeast)
  • Synonyms
    1110059L23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916051
    NCBI Gene: 68801
  • Gene Overview
    MyGene.info: ELOVL5
  • Alliance
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:77917365-77984519 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 43.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    473 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916051
protein coding gene Chr9:77917364-77984519 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035055
protein coding gene Chr9:78377627-78450580 (+)
A/J MGP_AJ_G0035036
protein coding gene Chr9:75640779-75709618 (+)
AKR/J MGP_AKRJ_G0034965
protein coding gene Chr9:77439345-77509194 (+)
BALB/cJ MGP_BALBcJ_G0035028
protein coding gene Chr9:75318803-75388070 (+)
C3H/HeJ MGP_C3HHeJ_G0034737
protein coding gene Chr9:77955115-78026620 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035546
protein coding gene Chr9:80482505-80555107 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032457
protein coding gene Chr9:74877520-74943785 (+)
CAST/EiJ MGP_CASTEiJ_G0034059
protein coding gene Chr9:78293082-78365870 (+)
CBA/J MGP_CBAJ_G0034709
protein coding gene Chr9:83236906-83320909 (+)
DBA/2J MGP_DBA2J_G0034869
protein coding gene Chr9:75300525-75371172 (+)
FVB/NJ MGP_FVBNJ_G0034811
protein coding gene Chr9:74543859-74614602 (+)
LP/J MGP_LPJ_G0034950
protein coding gene Chr9:78608103-78683083 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034852
protein coding gene Chr9:84473868-84549194 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035569
protein coding gene Chr9:77615627-77684371 (+)
PWK/PhJ MGP_PWKPhJ_G0033763
protein coding gene Chr9:75532493-75598523 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033596
protein coding gene Chr9:77845099-77911224 (+)
WSB/EiJ MGP_WSBEiJ_G0034171
protein coding gene Chr9:77537898-77609456 (+)



Homology
more
  • Human Ortholog
    ELOVL5, ELOVL fatty acid elongase 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ELOVL5, ELOVL fatty acid elongase 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ483K16.1, HELO1, SCA38
  • Links
    NCBI Gene ID: 60481
    neXtProt AC: NX_Q9NYP7
    UniProt: Q9NYP7

  • Chr Location
    6p12.1; chr6:53267398-53349179 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ELOVL5 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele have defects in fatty acid synthesis in the liver that result in hepatic steatosis. Also, majority of female mice have defects in female fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68801 NCBI Gene Model | MGI Sequence Detail 67155 C57BL/6J ±  kb
    transcript NM_134255 RefSeq | MGI Sequence Detail 2802 C57BL/6  
    polypeptide Q8BHI7 UniProt | EBI | MGI Sequence Detail 299 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 20
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2143114, MGI:2143235
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 4
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
    • Latest
      J:216600 Lau CG, et al., Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil. Mol Reprod Dev. 2014 Nov;81(11):994-1008

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory