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Elovl5
Gene Detail
Symbol

Name
ID
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
MGI:1916051
Synonyms
1110059L23Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
43.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:77917364-77984519 bp, + strand
From VEGA annotation of GRCm38

  67156 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41449  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Elovl5

Human
homologs
Human Homolog ELOVL5, ELOVL fatty acid elongase 5
NCBI Gene ID 60481
neXtProt AC  NX_Q9NYP7
Human Synonyms  dJ483K16.1, HELO1, SCA38
Human Chr (Location)  6p21.1-p12.1; chr6:53267398-53349179 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ELOVL5
Mutations,
alleles, and
phenotypes
All mutations/alleles(149) : Gene trapped(146) Radiation induced(1) Targeted(2)
Genomic Mutations involving Elovl5 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele have defects in fatty acid synthesis in the liver that result in hepatic steatosis. Also, majority of female mice have defects in female fertility.
 
Interactions
Elovl5 interacts with 308 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (96)    Tissues (95)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
RT-PCR 2
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(18) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022986 (Evidence)
Ensembl Gene ModelENSMUSG00000032349 (Evidence)
Entrez Gene68801 (Evidence)
DFCITC1573390
DoTSDT.101737958, DT.101381056, DT.91360977, DT.534201
NIA Mouse Gene IndexU010772
EC2.3.1.199
Consensus CDS ProjectCCDS23355.1
International Mouse Knockout Project StatusElovl5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022986 VEGA Gene Model | MGI Sequence Detail 67156 C57BL/6J ±  kb
transcript OTTMUST00000055326 VEGA | MGI Sequence Detail 2782 Not Applicable 
polypeptide OTTMUSP00000026486 VEGA | MGI Sequence Detail 299 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(8) UniProt(7)
Polymorphisms
SNPs within 2kb(476 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002076 GNS1/SUR4 membrane protein
Protein Ontology PR:000007040 elongation of very long chain fatty acids protein 5
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:210042 Ichi I, et al., Identification of genes and pathways involved in the synthesis of Mead acid (20:3n-9), an indicator of essential fatty acid deficiency. Biochim Biophys Acta. 2014 Jan;1841(1):204-13
All references(44)
Other
accession IDs
MGI:2143114, MGI:2143235

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory