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Rab3gap2 Gene Detail
Summary
  • Symbol
    Rab3gap2
  • Name
    RAB3 GTPase activating protein subunit 2
  • Synonyms
    1110059F07Rik, mKIAA0839
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916043
    NCBI Gene: 98732
  • Gene Overview
    MyGene.info: RAB3GAP2
Location & Maps
more
  • Sequence Map
    Chr1:185204117-185286759 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      82643 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RAB3GAP2, RAB3 GTPase activating non-catalytic protein subunit 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RAB3GAP2, RAB3 GTPase activating non-catalytic protein subunit 2
    Orthology source: HomoloGene
  • Synonyms
    p150, RAB3GAP150, RAB3-GAP150, SPG69, WARBM2
  • Links
    NCBI Gene ID: 25782
    neXtProt AC: NX_Q9H2M9

  • Chr Location
    1q41; chr1:220148268-220272501 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human RAB3GAP2 associations

Human Disease Mouse Models
       Martsolf Syndrome   OMIM: 212720
Warburg Micro Syndrome 2; WARBM2   OMIM: 614225
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050654 VEGA Gene Model | MGI Sequence Detail 82643 C57BL/6J ±  kb
transcript OTTMUST00000128410 VEGA | MGI Sequence Detail 7052 Not Applicable  
polypeptide OTTMUSP00000069079 VEGA | MGI Sequence Detail 1387 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    993 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000013622 rab3 GTPase-activating protein non-catalytic subunit
  • InterPro Domains
    IPR026059 Rab3-GAP regulatory subunit
    IPR029257 Rab3GAP regulatory subunit, C-terminal
    IPR032839 Rab3-GAP regulatory subunit, N-terminal
Molecular
Reagents
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  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
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MGI:2138353, MGI:2138627
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory