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Tmem53 Gene Detail
Summary
  • Symbol
    Tmem53
  • Name
    transmembrane protein 53
  • Synonyms
    1110038M16Rik, 1500001P22Rik, 1700012A05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916027
    NCBI Gene: 68777
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117251951-117268582 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.43 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    117 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916027
protein coding gene Chr4:117251951-117268588 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028649
protein coding gene Chr4:118222510-118241963 (+)
A/J MGP_AJ_G0028610
protein coding gene Chr4:113657876-113673957 (+)
AKR/J MGP_AKRJ_G0028560
protein coding gene Chr4:116143115-116163744 (+)
BALB/cJ MGP_BALBcJ_G0028631
protein coding gene Chr4:114288538-114306006 (+)
C3H/HeJ MGP_C3HHeJ_G0028345
protein coding gene Chr4:117730780-117754827 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029072
protein coding gene Chr4:122783835-122811436 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026356
protein coding gene Chr4:107701062-107716677 (+)
CAST/EiJ MGP_CASTEiJ_G0027779
protein coding gene Chr4:114932436-114952756 (+)
CBA/J MGP_CBAJ_G0028312
protein coding gene Chr4:126145378-126163887 (+)
DBA/2J MGP_DBA2J_G0028460
protein coding gene Chr4:114292397-114308230 (+)
FVB/NJ MGP_FVBNJ_G0028428
protein coding gene Chr4:112799121-112815897 (+)
LP/J MGP_LPJ_G0028562
protein coding gene Chr4:118400574-118417763 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028455
protein coding gene Chr4:131087797-131108052 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029109
protein coding gene Chr4:117296713-117314782 (+)
PWK/PhJ MGP_PWKPhJ_G0027505
protein coding gene Chr4:111099460-111116002 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027328
protein coding gene Chr4:113614646-113632467 (+)
WSB/EiJ MGP_WSBEiJ_G0027858
protein coding gene Chr4:117175771-117196195 (+)



Homology
more
  • Human Ortholog
    TMEM53, transmembrane protein 53
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM53, transmembrane protein 53
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NET4
  • Links
    NCBI Gene ID: 79639
    neXtProt AC: NX_Q6P2H8
    UniProt: Q6P2H8

  • Chr Location
    1p34.1; chr1:44653247-44674608 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41573
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMEM53
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Tmem53
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048772 Ensembl Gene Model | MGI Sequence Detail 16632 C57BL/6J ±  kb
transcript ENSMUST00000106434 Ensembl | MGI Sequence Detail 923 Not Applicable  
polypeptide ENSMUSP00000102042 Ensembl | MGI Sequence Detail 283 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916223, MGI:1923634
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory