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Zc3hc1 Gene Detail
Summary
  • Symbol
    Zc3hc1
  • Name
    zinc finger, C3HC type 1
  • Synonyms
    1110054L24Rik, HSPC216, Nipa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916023
    NCBI Gene: 232679
  • Gene Overview
    MyGene.info: ZC3HC1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:30366380-30391028 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 12.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916023
protein coding gene Chr6:30366380-30391040 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030535
protein coding gene Chr6:28243805-28270367 (-)
A/J MGP_AJ_G0030508
protein coding gene Chr6:27029560-27054729 (-)
AKR/J MGP_AKRJ_G0030435
protein coding gene Chr6:27931661-27958202 (-)
BALB/cJ MGP_BALBcJ_G0030518
protein coding gene Chr6:27183885-27208195 (-)
C3H/HeJ MGP_C3HHeJ_G0030231
protein coding gene Chr6:27921371-27947972 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030972
protein coding gene Chr6:29051752-29076139 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028183
protein coding gene Chr6:25230264-25252537 (-)
CAST/EiJ MGP_CASTEiJ_G0029633
protein coding gene Chr6:27750423-27775469 (-)
CBA/J MGP_CBAJ_G0030209
protein coding gene Chr6:30146606-30173619 (-)
DBA/2J MGP_DBA2J_G0030353
protein coding gene Chr6:26960844-26986551 (-)
FVB/NJ MGP_FVBNJ_G0030307
protein coding gene Chr6:26726410-26750807 (-)
LP/J MGP_LPJ_G0030440
protein coding gene Chr6:28379631-28406620 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030343
protein coding gene Chr6:32602788-32630357 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031002
protein coding gene Chr6:27813328-27838396 (-)
PWK/PhJ MGP_PWKPhJ_G0029347
protein coding gene Chr6:26535274-26559919 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029183
protein coding gene Chr6:27549645-27576291 (-)
WSB/EiJ MGP_WSBEiJ_G0029709
protein coding gene Chr6:27781808-27808569 (-)



Homology
more
  • Human Ortholog
    ZC3HC1, zinc finger C3HC-type containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZC3HC1, zinc finger C3HC-type containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC216, NIPA
  • Links
    NCBI Gene ID: 51530
    neXtProt AC: NX_Q86WB0
    UniProt: Q86WB0

  • Chr Location
    7q32.2; chr7:130018286-130051451 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    34 phenotypes from 2 alleles in 3 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display partial lethality with male infertility, reduced female fertility, arrest of meiosis, impaired synaptonemal complex formation and delayed double strand DNA break repair.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039130 Ensembl Gene Model | MGI Sequence Detail 24649 C57BL/6J ±  kb
transcript ENSMUST00000080812 Ensembl | MGI Sequence Detail 1824 Not Applicable  
polypeptide ENSMUSP00000079627 Ensembl | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 87
    cDNA 87

    Microarray probesets 3
Other
Accession IDs
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MGI:2141556, MGI:2141563
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:185584 Illert AL, et al., Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase. Development. 2012 Jul;139(14):2523-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory