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Zc3hc1
Gene Detail
Symbol

Name
ID
Zc3hc1
zinc finger, C3HC type 1
MGI:1916023
Synonyms
1110054L24Rik, HSPC216, Nipa
Feature Type
protein coding gene
Genetic Map
Chromosome 6
12.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:30366380-30391028 bp, - strand
From VEGA annotation of GRCm38

  24649 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32315  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zc3hc1

Human
homologs
Human Homolog ZC3HC1, zinc finger, C3HC-type containing 1
NCBI Gene ID 51530
neXtProt AC  NX_Q86WB0
Human Synonyms  NIPA
Human Chr (Location)  7q32.2; chr7:130018286-130051451 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(11) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display partial lethality with male infertility, reduced female fertility, arrest of meiosis, impaired synaptonemal complex formation and delayed double strand DNA break repair.
 
Interactions
Zc3hc1 interacts with 123 markers (Mir15a, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell cycle, cell division, ...
Component nuclear membrane, nucleus
Function metal ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(85)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(86) cDNA(86)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000014349 (Evidence)
Ensembl Gene ModelENSMUSG00000039130 (Evidence)
Entrez Gene232679 (Evidence)
UniGene29780
DFCITC1574153, TC1594890, TC1601125
DoTSDT.91344869, DT.94313167, DT.99846630
NIA Mouse Gene IndexU027120
Consensus CDS ProjectCCDS19970.1
International Mouse Knockout Project StatusZc3hc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014349 VEGA Gene Model | MGI Sequence Detail 24649 C57BL/6J ±  kb
transcript OTTMUST00000033905 VEGA | MGI Sequence Detail 1824 Not Applicable 
polypeptide OTTMUSP00000015183 VEGA | MGI Sequence Detail 501 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(6) UniProt(6)
Polymorphisms
SNPs within 2kb(83 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013909 Nuclear-interacting partner of ALK/Rsm1-like
InterPro IPR012935 Zinc finger, C3HC-like
Protein Ontology PR:000017603 nuclear-interacting partner of ALK
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:185584 Illert AL, et al., Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase. Development. 2012 Jul;139(14):2523-34
All references(41)
Other
accession IDs
MGI:2141556, MGI:2141563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory